H Towler1, M de la Fuente, S Lightman. 1. Department of Clinical Ophthalmology, Moorfields Eye Hospital, Institute of Ophthalmology, London, UK.
Abstract
PURPOSE: To describe the features of posterior uveitis in patients who either developed or were known to have, biopsy-proven Hodgkin's disease (HD). METHODS: Four patients were identified who were attending the uveitis clinic. Their charts were reviewed retrospectively and information on their HD was obtained from other hospitals where necessary. Their case histories are presented. RESULTS: Two patients presented with uveitis prior to the diagnosis of HD and in the other two, the HD was thought to be in remission. The commonest ocular signs were of vitritis and discrete, white, chorioretinal lesions. No difference in the ocular findings were apparent between those who had a known diagnosis of HD and the those that did not. CONCLUSIONS: HD can occur in the eye and can mimic posterior uveitis. In two of the patients, the uveitis preceded the diagnosis of HD and at the time of presentation all investigations were normal. No specific diagnostic features were apparent, though three of the patients had vitritis and chorioretinal lesions.
PURPOSE: To describe the features of posterior uveitis in patients who either developed or were known to have, biopsy-proven Hodgkin's disease (HD). METHODS: Four patients were identified who were attending the uveitis clinic. Their charts were reviewed retrospectively and information on their HD was obtained from other hospitals where necessary. Their case histories are presented. RESULTS: Two patients presented with uveitis prior to the diagnosis of HD and in the other two, the HD was thought to be in remission. The commonest ocular signs were of vitritis and discrete, white, chorioretinal lesions. No difference in the ocular findings were apparent between those who had a known diagnosis of HD and the those that did not. CONCLUSIONS:HD can occur in the eye and can mimic posterior uveitis. In two of the patients, the uveitis preceded the diagnosis of HD and at the time of presentation all investigations were normal. No specific diagnostic features were apparent, though three of the patients had vitritis and chorioretinal lesions.
Authors: Juan Valenzuela; Jose J Echegaray; Emilio Dodds; Shree K Kurup; Careen Lowder; Sarah L Ondrejka; Arun D Singh Journal: Ocul Oncol Pathol Date: 2021-08-17