M A Lemp1. 1. Department of Ophthalmology, Georgetown University, Washington, DC, USA. 74604.576@compuserve.com
Abstract
PURPOSE: To review developments in dry-eye research leading to new therapeutic possibilities and to suggest a prioritizing schema. METHODS: New development in our understanding of the pathogenesis, diagnoses, and treatment of dry-eye states have been reviewed along with the possible impact on new therapeutic approaches. RESULTS: A variety of approaches to the pathogenesis and degrees of dry-eye states have emerged, giving rise to significant new approaches to the treatment of these disorders. CONCLUSION: There are now new treatment possibilities. Ranking their development based on their fundamental reversal of disease mechanisms seems a reasonable approach with early therapeutic pay-off.
PURPOSE: To review developments in dry-eye research leading to new therapeutic possibilities and to suggest a prioritizing schema. METHODS: New development in our understanding of the pathogenesis, diagnoses, and treatment of dry-eye states have been reviewed along with the possible impact on new therapeutic approaches. RESULTS: A variety of approaches to the pathogenesis and degrees of dry-eye states have emerged, giving rise to significant new approaches to the treatment of these disorders. CONCLUSION: There are now new treatment possibilities. Ranking their development based on their fundamental reversal of disease mechanisms seems a reasonable approach with early therapeutic pay-off.