Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Improvement of the intestinal absorption of a peptidomimetic, boronic acid thrombin inhibitor possibly utilizing the oligopeptide transporter.

× No keyword cloud information.

11 in total

1. New inhibitors of thrombin and other trypsin-like proteases: hydrogen bonding of an aromatic cyano group with a backbone amide of the P1 binding site replaces binding of a basic side chain.

Authors: S L Lee; R S Alexander; A Smallwood; R Trievel; L Mersinger; P C Weber; C Kettner
Journal: Biochemistry Date: 1997-10-28 Impact factor: 3.162

2. Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration in rats.

Authors: M A Hussain; R Knabb; B J Aungst; C Kettner
Journal: Peptides Date: 1991 Sep-Oct Impact factor: 3.750

3. Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist.

Authors: B J Aungst; H Saitoh
Journal: Pharm Res Date: 1996-01 Impact factor: 4.200

4. Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine.

Authors: H Saitoh; H Fujisaki; B J Aungst; K Miyazaki
Journal: Pharm Res Date: 1997-05 Impact factor: 4.200

5. The secretory intestinal transport of some beta-lactam antibiotics and anionic compounds: a mechanism contributing to poor oral absorption.

Authors: H Saitoh; C Gerard; B J Aungst
Journal: J Pharmacol Exp Ther Date: 1996-07 Impact factor: 4.030

6. The selective inhibition of thrombin by peptides of boroarginine.

Authors: C Kettner; L Mersinger; R Knabb
Journal: J Biol Chem Date: 1990-10-25 Impact factor: 5.157

Review 7. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile.

Authors: C Tapparelli; R Metternich; C Ehrhardt; N S Cook
Journal: Trends Pharmacol Sci Date: 1993-10 Impact factor: 14.819

Review 8. Challenges in the development of orally bioavailable thrombin active site inhibitors.

Authors: S D Kimball
Journal: Blood Coagul Fibrinolysis Date: 1995-09 Impact factor: 1.276

9. Structural requirements for the intestinal mucosal-cell peptide transporter: the need for N-terminal alpha-amino group.

Authors: P F Bai; P Subramanian; H I Mosberg; G L Amidon
Journal: Pharm Res Date: 1991-05 Impact factor: 4.200

10. Molecular modeling study of structural requirements for the oligopeptide transporter.

Authors: J Li; I J Hidalgo
Journal: J Drug Target Date: 1996 Impact factor: 5.121