| Literature DB >> 10571165 |
C B Vu1, E G Corpuz, S G Pradeepan, S Violette, C Bartlett, T K Sawyer.
Abstract
The synthesis of a series of 1,2,4-oxadiazole analogs is discussed along with their ZAP-70 SH2 inhibitory activity. The tyrosine moiety in the original series has been replaced with nonpeptidic functional groups without a substantial loss of binding affinity.Entities:
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Year: 1999 PMID： 10571165 DOI： 10.1016/s0960-894x(99)00524-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823