| Literature DB >> 10571149 |
E A Couladouros1, T Li, V I Moutsos, E N Pitsinos, I C Soufli.
Abstract
The effect of five derivatives of Combretastatin D on tubulin polymerization was investigated. All of them were found to stabilize microtubules to various degrees. The derivatives bearing polar substituents were found to be the most active.Entities:
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Year: 1999 PMID： 10571149 DOI： 10.1016/s0960-894x(99)00503-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823