| Literature DB >> 10571146 |
J Lee1, S U Park, J Y Kim, J K Kim, J Lee1, U Oh, V E Marquez, M Beheshti, Q J Wang, S Modarres, P M Blumberg.
Abstract
A series of 3-acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid were designed and synthesized as vanilloid receptor agonists containing the three principal pharmacophores of resiniferatoxin. Amide analogues 23, 5 and 11 were found to be potent agonists in vanilloid receptor assay both for ligand binding and for activation.Entities:
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Year: 1999 PMID： 10571146 DOI： 10.1016/s0960-894x(99)00513-2
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823