Literature DB >> 10568117

The biological effects of magnetic stimulation in epileptic patients.

P A Anninos1, N Tsagas, J I Jacobson, A Kotini.   

Abstract

BACKGROUND: The magnetoencephalogram (MEG) is the magnetic activity emitted by the brain, which can be measured using a superconductive quantum interference device (SQUID). This is a totally non-invasive method for localizing functional healthy, epileptic and other CNS brain disorders.
METHODS: Using the MEG brain activity recorded from epileptic patients we were able to obtain a mapping technique characterized by the ISO-spectral amplitude of scalp distribution of the MEG Fourier power spectrum. In addition, by utilizing the above recorded MEG activity we energize an electronic device, which emits back to the abnormal brain points of the epileptic patients magnetic fields with proper frequencies and intensities.
RESULTS: Using this method we present here in more detail three randomly selected epileptic patients in which application of external magnetic fields of low intensities and frequencies produced a substantial attenuation of their abnormal brain activity. Furthermore, we present a statistical analysis of 50 randomly selected epileptic patients who underwent magnetic stimulation for the treatment of their seizures and we found that the anticonvulsant response to magnetic stimulation was statistically significant (chi 2 = 6.55, df = 1, p < 0.02).
CONCLUSIONS: Our findings indicate that the use of low external magnetic fields produce substantial attenuation in seizure activity in epileptic patients and therefore it may open new ways in the future for management of epileptic activity.

Entities:  

Mesh:

Year:  1999        PMID: 10568117

Source DB:  PubMed          Journal:  Panminerva Med        ISSN: 0031-0808            Impact factor:   5.197


  7 in total

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Journal:  Med Biol Eng Comput       Date:  2016-04-06       Impact factor: 2.602

2.  Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation.

Authors:  Hui Ye; Vincent Chen; Jenna Hendee
Journal:  Sci Rep       Date:  2022-07-15       Impact factor: 4.996

3.  Transmembrane potential induced on the internal organelle by a time-varying magnetic field: a model study.

Authors:  Hui Ye; Marija Cotic; Eunji E Kang; Michael G Fehlings; Peter L Carlen
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4.  We Used a Double Blind Experiment to Investigate Weak pT-TMS in Epilepsy Patients.

Authors:  Photios Anninos; Nicolia Anninou; Adam Adamopoulos; Athanasia Kotini; Triandafillos Gemousakakis; Nicolaos Tsagas
Journal:  Maedica (Bucur)       Date:  2020-03

5.  A comparative study of a theoretical neural net model with MEG data from epileptic patients and normal individuals.

Authors:  A Kotini; P Anninos; A N Anastasiadis; D Tamiolakis
Journal:  Theor Biol Med Model       Date:  2005-09-07       Impact factor: 2.432

6.  Vesicle biomechanics in a time-varying magnetic field.

Authors:  Hui Ye; Austen Curcuru
Journal:  BMC Biophys       Date:  2015-01-21       Impact factor: 4.778

7.  Emerging synergisms between drugs and physiologically-patterned weak magnetic fields: implications for neuropharmacology and the human population in the twenty-first century.

Authors:  P D Whissell; M A Persinger
Journal:  Curr Neuropharmacol       Date:  2007-12       Impact factor: 7.363

  7 in total

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