Literature DB >> 10567911

Modes of regulation of ubiquitin-mediated protein degradation.

D Kornitzer1, A Ciechanover.   

Abstract

The ubiquitin-proteasome pathway is responsible for the major portion of specific cellular protein degradation. Ubiquitin-mediated degradation is involved in physiological regulation of many cellular processes, including cell cycle progression, differentiation, and signal transduction. Here, we review the basic mechanisms of the ubiquitin system and the various ways in which ubiquitin-mediated degradation can be modulated by physiological signals. Copyright 2000 Wiley-Liss, Inc.

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Year:  2000        PMID： 10567911     DOI： 10.1002/(SICI)1097-4652(200001)182:1<1::AID-JCP1>3.0.CO;2-V

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  65 in total

1.  SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase.

Authors:  A Orian; H Gonen; B Bercovich; I Fajerman; E Eytan; A Israël; F Mercurio; K Iwai; A L Schwartz; A Ciechanover
Journal:  EMBO J       Date:  2000-06-01       Impact factor: 11.598

2.  Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

Authors:  F Osaka; M Saeki; S Katayama; N Aida; A Toh-E; K Kominami; T Toda; T Suzuki; T Chiba; K Tanaka; S Kato
Journal:  EMBO J       Date:  2000-07-03       Impact factor: 11.598

Review 3.  Ubiquitin-mediated proteolysis in learning and memory.

Authors:  D G Chain; J H Schwartz; A N Hegde
Journal:  Mol Neurobiol       Date:  1999 Oct-Dec       Impact factor: 5.590

Review 4.  What is the function of receptor and membrane endocytosis at the postsynaptic neuron?

Authors:  J Smythies
Journal:  Proc Biol Sci       Date:  2000-07-07       Impact factor: 5.349

5.  The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity.

Authors:  Maria Luisa Gándara; Pilar López; Raquel Hernando; José G Castaño; Susana Alemany
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

6.  Replication-initiator protein (UL9) of the herpes simplex virus 1 binds NFB42 and is degraded via the ubiquitin-proteasome pathway.

Authors:  Chi-Yong Eom; I Robert Lehman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-06       Impact factor: 11.205

7.  Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property.

Authors:  Hao G Nguyen; Dharmaraj Chinnappan; Takeshi Urano; Katya Ravid
Journal:  Mol Cell Biol       Date:  2005-06       Impact factor: 4.272

8.  Taxol and tau overexpression induced calpain-dependent degradation of the microtubule-destabilizing protein SCG10.

Authors:  Irving E Vega; Tadanori Hamano; Josh A Propost; Gabriele Grenningloh; Shu-Hui Yen
Journal:  Exp Neurol       Date:  2006-07-05       Impact factor: 5.330

Review 9.  Roles of TRAF6 in CD40 signaling.

Authors:  Bruce S Hostager
Journal:  Immunol Res       Date:  2007       Impact factor: 2.829

10.  Chronic ethanol feeding affects proteasome-interacting proteins.

Authors:  Marie-Pierre Bousquet-Dubouch; Sheila Nguen; David Bouyssié; Odile Burlet-Schiltz; Samuel W French; Bernard Monsarrat; Fawzia Bardag-Gorce
Journal:  Proteomics       Date:  2009-07       Impact factor: 3.984
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