Literature DB >> 10565928

Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic Ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticks.

N Pusterla1, C M Leutenegger, J S Chae, H Lutz, R B Kimsey, J S Dumler, J E Madigan.   

Abstract

This paper describes the kinetics of the human granulocytic ehrlichiosis agent in the blood of horses experimentally infected by intravenous inoculation with infected leukocytes and by infected ticks as evaluated by using a real-time quantitative PCR assay. The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection.

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Year:  1999        PMID: 10565928      PMCID: PMC85876     

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  18 in total

1.  Infectivity of Borrelia burgdorferi relative to route of inoculation and genotype in laboratory mice.

Authors:  S W Barthold
Journal:  J Infect Dis       Date:  1991-02       Impact factor: 5.226

2.  Seroepidemiologic survey of antibodies to Ehrlichia equi in horses of northern California.

Authors:  J E Madigan; S Hietala; S Chalmers; E DeRock
Journal:  J Am Vet Med Assoc       Date:  1990-06-15       Impact factor: 1.936

3.  Duration of tick attachment required for transmission of granulocytic ehrlichiosis.

Authors:  P Katavolos; P M Armstrong; J E Dawson; S R Telford
Journal:  J Infect Dis       Date:  1998-05       Impact factor: 5.226

Review 4.  Ehrlichiosis.

Authors:  C L Fritz; C A Glaser
Journal:  Infect Dis Clin North Am       Date:  1998-03       Impact factor: 5.982

5.  Quantitative real-time PCR for detection of members of the Ehrlichia phagocytophila genogroup in host animals and Ixodes ricinus ticks.

Authors:  N Pusterla; J B Huder; C M Leutenegger; U Braun; J E Madigan; H Lutz
Journal:  J Clin Microbiol       Date:  1999-05       Impact factor: 5.948

6.  Variant responses of mice to Borrelia burgdorferi depending on the site of intradermal inoculation.

Authors:  M S de Souza; A L Smith; D S Beck; L J Kim; G M Hansen; S W Barthold
Journal:  Infect Immun       Date:  1993-10       Impact factor: 3.441

Review 7.  The tribe Ehrlichieae and ehrlichial diseases.

Authors:  Y Rikihisa
Journal:  Clin Microbiol Rev       Date:  1991-07       Impact factor: 26.132

8.  Mode of inoculation of the Lyme disease agent Borrelia burgdorferi influences infection and immune responses in inbred strains of mice.

Authors:  L Gern; U E Schaible; M M Simon
Journal:  J Infect Dis       Date:  1993-04       Impact factor: 5.226

9.  Distinct patterns of protective antibodies are generated against Borrelia burgdorferi in mice experimentally inoculated with high and low doses of antigen.

Authors:  U E Schaible; L Gern; R Wallich; M D Kramer; M Prester; M M Simon
Journal:  Immunol Lett       Date:  1993-05       Impact factor: 3.685

10.  Acquisition and transmission of the agent of human granulocytic ehrlichiosis by Ixodes scapularis ticks.

Authors:  E Hodzic; D Fish; C M Maretzki; A M De Silva; S Feng; S W Barthold
Journal:  J Clin Microbiol       Date:  1998-12       Impact factor: 5.948

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  12 in total

1.  Evaluation of a PCR assay for quantitation of Rickettsia rickettsii and closely related spotted fever group rickettsiae.

Authors:  Marina E Eremeeva; Gregory A Dasch; David J Silverman
Journal:  J Clin Microbiol       Date:  2003-12       Impact factor: 5.948

2.  Dexamethasone-induced cytokine changes associated with diminished disease severity in horses infected with Anaplasma phagocytophilum.

Authors:  R S Davies; J E Madigan; E Hodzic; D L Borjesson; J S Dumler
Journal:  Clin Vaccine Immunol       Date:  2011-08-31

3.  Infection with Anaplasma phagocytophilum induces multilineage alterations in hematopoietic progenitor cells and peripheral blood cells.

Authors:  J L Johns; K C Macnamara; N J Walker; G M Winslow; D L Borjesson
Journal:  Infect Immun       Date:  2009-06-29       Impact factor: 3.441

4.  Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks.

Authors:  Ning Zhi; Norio Ohashi; Tomoko Tajima; Jason Mott; Roger W Stich; Debra Grover; Sam R Telford; Quan Lin; Yasuko Rikihisa
Journal:  Infect Immun       Date:  2002-03       Impact factor: 3.441

5.  Immunopathology and ehrlichial propagation are regulated by interferon-gamma and interleukin-10 in a murine model of human granulocytic ehrlichiosis.

Authors:  M E Martin; K Caspersen; J S Dumler
Journal:  Am J Pathol       Date:  2001-05       Impact factor: 4.307

6.  Cytokine gene expression by peripheral blood leukocytes in horses experimentally infected with Anaplasma phagocytophila.

Authors:  Hyung-Yong Kim; Jason Mott; Ning Zhi; Tomoko Tajima; Yasuko Rikihisa
Journal:  Clin Diagn Lab Immunol       Date:  2002-09

7.  Reinfection with Anaplasma phagocytophilum in BALB/c mice and cross-protection between two sympatric isolates.

Authors:  Michael L Levin; Dondrae J Coble; Danielle E Ross
Journal:  Infect Immun       Date:  2004-08       Impact factor: 3.441

8.  Kinetics of experimental infection of sheep with Ehrlichia ruminantium cultivated in tick and mammalian cell lines.

Authors:  Milagros Postigo; Lesley Bell-Sakyi; Edith Paxton; Keith Sumption
Journal:  Exp Appl Acarol       Date:  2002       Impact factor: 2.132

9.  Superinfection occurs in Anaplasma phagocytophilum infected sheep irrespective of infection phase and protection status.

Authors:  Snorre Stuen; Wenche O Torsteinbø; Karin Bergström; Kjetil Bårdsen
Journal:  Acta Vet Scand       Date:  2009-10-26       Impact factor: 1.695

10.  Seasonal dynamics of Anaplasma phagocytophila in a rodent-tick (Ixodes trianguliceps) system, United Kingdom.

Authors:  Kevin J Bown; Michael Begon; Malcolm Bennett; Zerai Woldehiwet; Nicholas H Ogden
Journal:  Emerg Infect Dis       Date:  2003-01       Impact factor: 6.883

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