Literature DB >> 10565524

Is neuroprotection a viable therapy for glaucoma?

R N Weinreb1, L A Levin.   

Abstract

Treatment of glaucoma continues to be directed at lowering intraocular pressure to decrease the likelihood of disease progression. In the future intraocular pressure reduction might be augmented by other therapeutic approaches. Interest has been increasing in preventing progression of glaucomatous optic neuropathy using approaches based on the premise that glaucoma is a neurodegenerative disease. Neuroprotection of the glaucomatous optic nerve therefore would be an adjuctive therapeutic paradigm for use with conventional intraocular pressure-lowering treatments or by itself.

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Year:  1999        PMID: 10565524     DOI: 10.1001/archopht.117.11.1540

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  25 in total

1.  Female reproductive factors and open angle glaucoma: the Blue Mountains Eye Study.

Authors:  A J Lee; P Mitchell; E Rochtchina; P R Healey
Journal:  Br J Ophthalmol       Date:  2003-11       Impact factor: 4.638

2.  The bugeye mutant zebrafish exhibits visual deficits that arise with the onset of an enlarged eye phenotype.

Authors:  Joseph M Stujenske; John E Dowling; Farida Emran
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-06-13       Impact factor: 4.799

Review 3.  Glaucoma medications: use and safety in the elderly population.

Authors:  Elliott Kanner; James C Tsai
Journal:  Drugs Aging       Date:  2006       Impact factor: 3.923

4.  Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucoma.

Authors:  H Schori; J Kipnis; E Yoles; E WoldeMussie; G Ruiz; L A Wheeler; M Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-06       Impact factor: 11.205

5.  Edible seaweed, Eisenia bicyclis, protects retinal ganglion cells death caused by oxidative stress.

Authors:  Kyung-A Kim; Sang Min Kim; Suk Woo Kang; Sang Il Jeon; Byung Hun Um; Sang Hoon Jung
Journal:  Mar Biotechnol (NY)       Date:  2012-05-18       Impact factor: 3.619

6.  Enhancement of scleral macromolecular permeability with prostaglandins.

Authors:  R N Weinreb
Journal:  Trans Am Ophthalmol Soc       Date:  2001

7.  Genotype and phenotype correlations in congenital glaucoma.

Authors:  David A Hollander; Mansoor Sarfarazi; Ivaylo Stoilov; Irmgard S Wood; Douglas R Fredrick; Jorge A Alvarado
Journal:  Trans Am Ophthalmol Soc       Date:  2006

Review 8.  Neuroprotection for treatment of glaucoma in adults.

Authors:  Dayse F Sena; Kristina Lindsley
Journal:  Cochrane Database Syst Rev       Date:  2013-02-28

9.  Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension.

Authors:  Anna Galanopoulos; Ivan Goldberg
Journal:  Clin Ophthalmol       Date:  2009-06-02

10.  Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs.

Authors:  José Melena; Neville N Osborne
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-07-29       Impact factor: 3.117

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