Literature DB >> 105644

Phenylethylamine in rhesus monkeys: interactions with alpha-methyl-para-tyrosine and l-dopa.

J R Tinklenberg, J C Gillin, G M Murphy, R Staub, R J Wyatt.   

Abstract

Rhesus monkeys, pretreated with alpha-methyl-para-tryosine (AMPT) and subsequently injected with phenylethylamine (PEA), did not demonstrate the characteristic amphetamine-like PEA effects. However, when AMPT pretreatment was followed with l-dopa and then PEA injection, PEA effects were restored. These results are compatible with a dopamine theory of schizophrenia.

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Year:  1979        PMID: 105644     DOI: 10.1176/ajp.136.3.311

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  1 in total

1.  A study on the acute effect of amphetamine on the urinary excretion of biogenic amines and metabolites in monkeys.

Authors:  L W Chuang; F Karoum; M J Perlow
Journal:  Br J Pharmacol       Date:  1981-11       Impact factor: 8.739

  1 in total

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