| Literature DB >> 105644 |
J R Tinklenberg, J C Gillin, G M Murphy, R Staub, R J Wyatt.
Abstract
Rhesus monkeys, pretreated with alpha-methyl-para-tryosine (AMPT) and subsequently injected with phenylethylamine (PEA), did not demonstrate the characteristic amphetamine-like PEA effects. However, when AMPT pretreatment was followed with l-dopa and then PEA injection, PEA effects were restored. These results are compatible with a dopamine theory of schizophrenia.Entities:
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Year: 1979 PMID: 105644 DOI: 10.1176/ajp.136.3.311
Source DB: PubMed Journal: Am J Psychiatry ISSN: 0002-953X Impact factor: 18.112