Literature DB >> 10563690

The treatment of paediatric burns using topical papaya.

I F Starley1, P Mohammed, G Schneider, S W Bickler.   

Abstract

Due to the limited resources for the management of burns in most regions of Africa there is a significant role for many aspects of traditional African medicine. The active component of many traditional preparations is often of plant origin and more than 25 plants have been described as useful in relations to burns and wound healing. Carica papaya is currently used in The Gambia at the Royal Victoria Hospital, Banjul in the Paediatric Unit as the major component of burns dressings, where it is well tolerated by the children. Cheap and widely available, the pulp of the papaya fruit is mashed and applied daily to full thickness and infected burns. It appears to be effective in desloughing necrotic tissue, preventing burn wound infection, and providing a granulating wound suitable for the application of a split thickness skin graft. Possible mechanisms of action include the activity of proteolytic enzymes chymopapain and papain, as well as an antimicrobial activity, although further studies are required.

Entities:  

Mesh:

Year:  1999        PMID: 10563690     DOI: 10.1016/s0305-4179(99)00056-x

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  17 in total

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2.  Optimizing Burn Treatment in Developing Low-and Middle-Income Countries with Limited Health Care Resources (Part 3).

Authors:  B Atiyeh; A Masellis; F Conte
Journal:  Ann Burns Fire Disasters       Date:  2010-03-31

3.  Bromelain-based enzymatic debridement and minimal invasive modality (mim) care of deeply burned hands.

Authors:  Y Krieger; G Rubin; A Schulz; N Rosenberg; A Levi; A J Singer; L Rosenberg; Y Shoham
Journal:  Ann Burns Fire Disasters       Date:  2017-09-30

Review 4.  Open burn wound dressing: a practical option in resource constrained settings.

Authors:  O A Olawoye; O O Osinupebi; B A Ayoade
Journal:  Ann Burns Fire Disasters       Date:  2013-09-30

Review 5.  Topical antimicrobials for burn wound infections.

Authors:  T Dai; Y Y Huang; S K Sharma; J T Hashmi; D B Kurup; M R Hamblin
Journal:  Recent Pat Antiinfect Drug Discov       Date:  2010-06

6.  Development of biscuits supplemented with papaya seed and peel: effects on physicochemical properties, bioactive compounds, in vitro absorption capacities and starch digestibility.

Authors:  Guihun Jiang; Xiaoyu Feng; Chen Zhao; Kashif Ameer; Zhaogen Wu
Journal:  J Food Sci Technol       Date:  2021-05-25       Impact factor: 2.701

7.  Bacteriotherapy with Lactobacillus plantarum in burns.

Authors:  Maria C Peral; Miguel A Huaman Martinez; Juan C Valdez
Journal:  Int Wound J       Date:  2009-02       Impact factor: 3.315

8.  Genotoxic and Cytotoxic Safety Evaluation of Papain (Carica papaya L.) Using In Vitro Assays.

Authors:  Claudia R da Silva; Marcia B N Oliveira; Ellen S Motta; Gabriella S de Almeida; Leandro L Varanda; Marcelo de Pádula; Alvaro C Leitão; Adriano Caldeira-de-Araújo
Journal:  J Biomed Biotechnol       Date:  2010-05-20

Review 9.  Upper Extremity Burns in the Developing World: A Neglected Epidemic.

Authors:  Sarah E Sasor; Kevin C Chung
Journal:  Hand Clin       Date:  2019-11       Impact factor: 1.907

10.  Comparison of safety and efficacy of papaya dressing with hydrogen peroxide solution on wound bed preparation in patients with wound gape.

Authors:  Mangala B Murthy; Bhasker K Murthy; Sanjay Bhave
Journal:  Indian J Pharmacol       Date:  2012 Nov-Dec       Impact factor: 1.200

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