| Literature DB >> 10563557 |
N J Robinson1, D Mulder, B Auvert, J Whitworth, R Hayes.
Abstract
The objective was to estimate the likely percentage of HIV infections that may be attributable to one-off partnerships (such as those between female sex workers and their clients) and longer-term partnerships in rural Uganda. This was addressed by the application of a microsimulation model (SimulAIDS) of the transmission dynamics of HIV infection, drawing on data from a population cohort of 10,000 in rural Uganda. For a scenario reproducing documented characteristics of the study population in 1990, when adult HIV prevalence was 9%, and during subsequent follow up (1990-1994), when adult HIV incidence was 8 per 1000 person-years, the percentage of HIV infections in men (women) attributed to one-off partnerships decreased from 96% (26%) during 1980 to 67% (8%) in 1989 and 22% (5%) in 1994. Reducing HIV transmission between one-off partners early in an HIV epidemic may substantially limit the potential for the spread of HIV infection. At a later phase, prevention must also focus on control of transmission between longer-term HIV-discordant partners.Entities:
Keywords: Acquired Immunodeficiency Syndrome; Africa; Africa South Of The Sahara; Behavior; Cohort Analysis; Demographic Factors; Developing Countries; Diseases; Eastern Africa; English Speaking Africa; Hiv Infections; Models, Theoretical; Population; Population Characteristics; Prostitutes; Research Methodology; Research Report; Rural Population; Sex Behavior; Sexual Partners; Uganda; Viral Diseases
Mesh：
Year: 1999 PMID： 10563557 DOI： 10.1258/0956462991913394
Source DB: PubMed Journal: Int J STD AIDS ISSN： 0956-4624 Impact factor: 1.359