E Vural1, J Y Suen, E Hanna. 1. Department of Otolaryngology, University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 543, Little Rock, AR 72205, USA.
Abstract
BACKGROUND: The purpose of this article is to define the outcome of intracranial extension of inverted papilloma and outline a rationale for management of this rare clinical presentation. METHODS: A review of patients with intracranial extension of inverted papilloma reported in the literature (18 patients), or treated in our institution (3 patients ) was performed. The data of these 21 patients were consolidated with regard to clinical presentation, treatment, and outcome. Nine patients, including 1 of our cases, had coexisting squamous cell carcinoma and therefore were excluded from the analysis. Twelve patients with "pure" inverted papilloma formed the basis of this study. RESULTS: The majority of patients (83%) with intracranial inverted papilloma had recurrent disease. Patients with extradural disease had a survival rate of 86% with an average follow-up of 4.4 years. Eighty-six percent of these survivors were treated with craniofacial resection. In contrast, 75% of patients with intradural inverted papilloma were dead of disease with an average follow-up of 9.3 months regardless of the treatment modality. CONCLUSIONS: Intracranial extension of inverted papilloma is mostly associated with recurrent disease. Intracranial extradural inverted papilloma can be effectively controlled with craniofacial resection. Intracranial intradural involvement of inverted papilloma has a poor prognosis regardless of treatment. Aggressive treatment of intranasal inverted papilloma may be the most important factor in preventing intracranial presentation. Copyright 1999 John Wiley & Sons, Inc. Head Neck 21: 703-706, 1999.
BACKGROUND: The purpose of this article is to define the outcome of intracranial extension of inverted papilloma and outline a rationale for management of this rare clinical presentation. METHODS: A review of patients with intracranial extension of inverted papilloma reported in the literature (18 patients), or treated in our institution (3 patients ) was performed. The data of these 21 patients were consolidated with regard to clinical presentation, treatment, and outcome. Nine patients, including 1 of our cases, had coexisting squamous cell carcinoma and therefore were excluded from the analysis. Twelve patients with "pure" inverted papilloma formed the basis of this study. RESULTS: The majority of patients (83%) with intracranial inverted papilloma had recurrent disease. Patients with extradural disease had a survival rate of 86% with an average follow-up of 4.4 years. Eighty-six percent of these survivors were treated with craniofacial resection. In contrast, 75% of patients with intradural inverted papilloma were dead of disease with an average follow-up of 9.3 months regardless of the treatment modality. CONCLUSIONS: Intracranial extension of inverted papilloma is mostly associated with recurrent disease. Intracranial extradural inverted papilloma can be effectively controlled with craniofacial resection. Intracranial intradural involvement of inverted papilloma has a poor prognosis regardless of treatment. Aggressive treatment of intranasal inverted papilloma may be the most important factor in preventing intracranial presentation. Copyright 1999 John Wiley & Sons, Inc. Head Neck 21: 703-706, 1999.
Authors: Poramate Pitak-Arnnop; Julia Bertolini; Kittipong Dhanuthai; Jörg Hendricks; Alexander Hemprich; Niels Christian Pausch Journal: Ger Med Sci Date: 2012-06-18
Authors: Kalla A Gervasio; Phoebe L Mellen; Ranjodh S Boparai; Rebecca R Soares; Judd Fastenberg; Mark Chaskes; Michael P Rabinowitz; Mindy R Rabinowitz Journal: Allergy Rhinol (Providence) Date: 2019-09-16
Authors: Ernest J Wright; Natalya Chernichenko; Eylem Ocal; Jennifer Moliterno; Ketan R Bulsara; Benjamin L Judson Journal: Skull Base Rep Date: 2011-09-29