| Literature DB >> 10560744 |
S De Jonghe1, I Van Overmeire, J Gunst, A De Bruyn, C Hendrix, S Van Calenbergh, R Busson, D De Keukeleire, J Philippé, P Herdewijn.
Abstract
Short-chain 3-fluoro-(dihydro)ceramide analogues are synthesized from L-serine using diethylaminosulfur trifluoride (DAST) as fluorinating agent. The apoptogenic activity of these compounds was measured in three different cell lines and compared with their hydroxylated counterparts.Entities:
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Year: 1999 PMID： 10560744 DOI： 10.1016/s0960-894x(99)00553-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823