Literature DB >> 10559903

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I.

M Kanzaki1, Y Q Zhang, H Mashima, L Li, H Shibata, I Kojima.   

Abstract

Calcium plays a critical part in the regulation of cell growth, and growth factors stimulate calcium entry into cells through calcium-permeable channels. However, the molecular nature and regulation of calcium-permeable channels are still unclear at present. Here we report the molecular characterization of a calcium-permeable cation channel that is regulated by insulin-like growth factor-I (IGF-I). This channel, which we name growth-factor-regulated channel (GRC), belongs to the TRP-channel family and localizes mainly to intracellular pools under basal conditions. Upon stimulation of cells by IGF-I, GRC translocates to the plasma membrane. Thus, IGF-I augments calcium entry through GRC by regulating trafficking of the channel.

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Year:  1999        PMID： 10559903     DOI： 10.1038/11086

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  143 in total

1.  Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry.

Authors:  G Boulay; D M Brown; N Qin; M Jiang; A Dietrich; M X Zhu; Z Chen; M Birnbaumer; K Mikoshiba; L Birnbaumer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

2.  Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells.

Authors:  L A Birder; A J Kanai; W C de Groat; S Kiss; M L Nealen; N E Burke; K E Dineley; S Watkins; I J Reynolds; M J Caterina
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-23       Impact factor: 11.205

3.  Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.

Authors:  Shouhong Xuan; Tadahiro Kitamura; Jun Nakae; Katerina Politi; Yoshiaki Kido; Peter E Fisher; Manrico Morroni; Saverio Cinti; Morris F White; Pedro L Herrera; Domenico Accili; Argiris Efstratiadis
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

4.  Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.

Authors:  Jose Mercado; Ariela Gordon-Shaag; William N Zagotta; Sharona E Gordon
Journal:  J Neurosci       Date:  2010-10-06       Impact factor: 6.167

5.  The presence of Ca2+ channel beta subunit is required for mitogen-activated protein kinase (MAPK)-dependent modulation of alpha1B Ca2+ channels in COS-7 cells.

Authors:  Elizabeth M Fitzgerald
Journal:  J Physiol       Date:  2002-09-01       Impact factor: 5.182

Review 6.  Intracellular calcium signals and control of cell proliferation: how many mechanisms?

Authors:  L Munaron; S Antoniotti; D Lovisolo
Journal:  J Cell Mol Med       Date:  2004 Apr-Jun       Impact factor: 5.310

Review 7.  Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP.

Authors:  D J Beech; K Muraki; R Flemming
Journal:  J Physiol       Date:  2004-07-22       Impact factor: 5.182

Review 8.  International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family.

Authors:  Long-Jun Wu; Tara-Beth Sweet; David E Clapham
Journal:  Pharmacol Rev       Date:  2010-09       Impact factor: 25.468

Review 9.  Invertebrate TRP proteins as functional models for mammalian channels.

Authors:  Joris Vriens; Grzegorz Owsianik; Thomas Voets; Guy Droogmans; Bernd Nilius
Journal:  Pflugers Arch       Date:  2004-12       Impact factor: 3.657

10.  Potentiation of quantal secretion by insulin-like growth factor-1 at developing motoneurons in Xenopus cell culture.

Authors:  Jau-Cheng Liou; Fong-Zu Tsai; Shih-Yin Ho
Journal:  J Physiol       Date:  2003-09-26       Impact factor: 5.182
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