Literature DB >> 10556971

The anti-apoptotic actions of nitric oxide in hepatocytes.

J Li1, T R Billiar.   

Abstract

Nitric oxide (NO) has anti-apoptotic actions in hepatocytes in vitro and in vivo. The protection is mediated via the S-nitrosylation of procaspases as well as the active caspase enzymes. NO stimulation of the cGMP/protein kinase G pathway also appears to contribute to the protective effect of NO. Here we review the evidence for the direct inhibition of NO with the apoptotic signaling pathways in hepatocytes.

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Year:  1999        PMID： 10556971     DOI： 10.1038/sj.cdd.4400579

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


  11 in total

1.  Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes.

Authors:  Hoe Suk Kim; Patricia A Loughran; Timothy R Billiar
Journal:  Nitric Oxide       Date:  2008-02-15       Impact factor: 4.427

2.  Distribution of nitric oxide synthase in normal and cirrhotic human liver.

Authors:  Lance McNaughton; Lakshmi Puttagunta; Maria Angeles Martinez-Cuesta; Norm Kneteman; Irvin Mayers; Redwan Moqbel; Qutayba Hamid; Marek W Radomski
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-13       Impact factor: 11.205

3.  Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP.

Authors:  Christopher M Schonhoff; Umadevi Ramasamy; M Sawkat Anwer
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-11-25       Impact factor: 4.052

Review 4.  Nitric oxide in liver inflammation and regeneration.

Authors:  Paloma Martin-Sanz; Sonsoles Hortelano; Nuria A Callejas; Nora Goren; Marta Casado; Miriam Zeini; Lisardo Boscá
Journal:  Metab Brain Dis       Date:  2002-12       Impact factor: 3.584

5.  Anemia and splenomegaly in cGKI-deficient mice.

Authors:  Michael Föller; Susanne Feil; Kamran Ghoreschi; Saisudha Koka; Andrea Gerling; Martin Thunemann; Franz Hofmann; Beat Schuler; Johannes Vogel; Bernd Pichler; Ravi S Kasinathan; Jan P Nicolay; Stephan M Huber; Florian Lang; Robert Feil
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-28       Impact factor: 11.205

6.  Preconditioning c-Kit-positive Human Cardiac Stem Cells with a Nitric Oxide Donor Enhances Cell Survival through Activation of Survival Signaling Pathways.

Authors:  Lei Teng; Edward Bennett; Chuanxi Cai
Journal:  J Biol Chem       Date:  2016-03-03       Impact factor: 5.157

7.  Inhibition of suicidal erythrocyte death by nitric oxide.

Authors:  Jan P Nicolay; Gerd Liebig; Olivier M Niemoeller; Saisudha Koka; Mehrdad Ghashghaeinia; Thomas Wieder; Judith Haendeler; Rudi Busse; Florian Lang
Journal:  Pflugers Arch       Date:  2007-12-06       Impact factor: 3.657

8.  Hypertonic saline and reduced peroxynitrite formation in experimental pancreatitis.

Authors:  Ester Correia Sarmento Rios; Ana Soares Moretti; Irineu Tadeu Velasco; Heraldo Possolo de Souza; Fatima Abatepaulo; Francisco Soriano
Journal:  Clinics (Sao Paulo)       Date:  2011       Impact factor: 2.365

Review 9.  Triggers, inhibitors, mechanisms, and significance of eryptosis: the suicidal erythrocyte death.

Authors:  Elisabeth Lang; Florian Lang
Journal:  Biomed Res Int       Date:  2015-03-04       Impact factor: 3.411

10.  First trimester placental endothelial cells from pregnancies with abnormal uterine artery Doppler are more sensitive to apoptotic stimuli.

Authors:  Nicoletta Charolidi; Amanda J Host; Sandra Ashton; Zoe Tryfonos; Karin Leslie; Baskaran Thilaganathan; Judith E Cartwright; Guy S Whitley
Journal:  Lab Invest       Date:  2018-10-05       Impact factor: 5.662
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