P Brooke1, R Bullock. 1. Kingshill Research Centre, Victoria Hospital, Swindon, UK.
Abstract
OBJECTIVE: To validate the 6 Item Cognitive Impairment Test (6CIT) against the Mini-Mental State Exam (MMSE) with a view to usage as a screening tool. DESIGN: Three groups with varying levels of dementia were tested using the MMSE, 6CIT and Global Deterioration Scale (GDS). SETTING: Testing was carried out within Wiltshire, both in the community and outpatients. SUBJECTS: Patients were selected from a hospital database of dementia patients and were stratified into two groups according to GDS; a control group was also tested. RESULTS: Two hundred and eighty-seven patients were tested: 135 controls (GDS 1-2), 70 with mild dementia (GDS 3-5) and 82 with more severe dementia (GDS 6-7). The 6CIT and MMSE were found to correlate well, r(2)=-0.911 (p<0.01), when all groups were analysed. Correlation falls to r(2)=-0.754 (p<0.01) in the mild dementia group. In the GDS 3-5 group, the MMSE has a sensitivity and specificity of 51.43% and 100% respectively (cutoff 23/24). The 6CIT gives a sensitivity and specificity of 78.57% and 100% (cutoff 7/8). CONCLUSION: The 6CIT is a brief and simple test of cognition, which correlates well with the MMSE but outperforms it in milder dementia. The MMSE is of little value as a screening test for dementia. Copyright 1999 John Wiley & Sons, Ltd.
OBJECTIVE: To validate the 6 Item Cognitive Impairment Test (6CIT) against the Mini-Mental State Exam (MMSE) with a view to usage as a screening tool. DESIGN: Three groups with varying levels of dementia were tested using the MMSE, 6CIT and Global Deterioration Scale (GDS). SETTING: Testing was carried out within Wiltshire, both in the community and outpatients. SUBJECTS:Patients were selected from a hospital database of dementiapatients and were stratified into two groups according to GDS; a control group was also tested. RESULTS: Two hundred and eighty-seven patients were tested: 135 controls (GDS 1-2), 70 with mild dementia (GDS 3-5) and 82 with more severe dementia (GDS 6-7). The 6CIT and MMSE were found to correlate well, r(2)=-0.911 (p<0.01), when all groups were analysed. Correlation falls to r(2)=-0.754 (p<0.01) in the mild dementia group. In the GDS 3-5 group, the MMSE has a sensitivity and specificity of 51.43% and 100% respectively (cutoff 23/24). The 6CIT gives a sensitivity and specificity of 78.57% and 100% (cutoff 7/8). CONCLUSION: The 6CIT is a brief and simple test of cognition, which correlates well with the MMSE but outperforms it in milder dementia. The MMSE is of little value as a screening test for dementia. Copyright 1999 John Wiley & Sons, Ltd.
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