Literature DB >> 10556680

The serotonin precursor 5-hydroxytryptophan elevates serum leptin levels in mice.

J Yamada1, Y Sugimoto, M Ujikawa.   

Abstract

The effects of a serotonin (5-HT) precursor 5-hydroxytryptophan (5-HTP) on serum leptin levels were investigated in mice. 5-HTP dose dependently increased serum leptin levels in mice. Pretreatment of the peripheral aromatic amino acid decarboxylase inhibitor carbidopa suppressed 5-HTP-induced hyperleptinemia. These results suggest that the secretion of leptin may be modified by serotonergic mechanisms.

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Year:  1999        PMID： 10556680     DOI： 10.1016/s0014-2999(99)00580-4

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  6 in total

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2.  Effect of escitalopram and carbidopa on bone markers in Wistar rats: a preliminary experimental study.

Authors:  Ravisha Wadhwa; Manoj Kumar; Yam Nath Paudel; Ramsha Iqbal; Priyanka Kothari; Ritu Trivedi; Divya Vohora
Journal:  J Bone Miner Metab       Date:  2018-01-29       Impact factor: 2.626

3.  Orexin A-induced inhibition of leptin expression and secretion in adipocytes reducing plasma leptin levels and hypothalamic leptin resistance.

Authors:  Su-Kyung Shin; Seung-Eun Song; Jin Uk Oh; Meeyul Hwang; Hyun-Woo Cho; Jae-Hoon Bae; Seung-Soon Im; Jee-In Kim; Dae-Kyu Song
Journal:  Pflugers Arch       Date:  2019-10-30       Impact factor: 3.657

4.  Serotonin and the regulation of mammalian energy balance.

Authors:  Michael H Donovan; Laurence H Tecott
Journal:  Front Neurosci       Date:  2013-03-27       Impact factor: 4.677

5.  Stimulation of leptin secretion by insulin.

Authors:  Minglun Tsai; Akihiro Asakawa; Haruka Amitani; Akio Inui
Journal:  Indian J Endocrinol Metab       Date:  2012-12

6.  5-HT1A/1B receptors as targets for optimizing pigmentary responses in C57BL/6 mouse skin to stress.

Authors:  Hua-Li Wu; Si-Lin Pang; Qiong-Zhen Liu; Qian Wang; Min-Xuan Cai; Jing Shang
Journal:  PLoS One       Date:  2014-02-21       Impact factor: 3.240
  6 in total

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