Literature DB >> 10556166

The macrophage in chronic obstructive pulmonary disease.

S D Shapiro1.   

Abstract

Macrophages are the predominant defense cell in the normal lung and during conditions associated with chronic inflammation such as COPD. However, the role of the macrophage in the development of COPD has been controversial. Scientific evidence from a variety of sources is emerging that supports a primary role for the macrophage in regulating the inflammatory response and tissue destruction associated with COPD. The role of macrophage proteinases in the development of emphysema, a major component of COPD, will be discussed. Shapiro SD. The macrophage in chronic obstructive pulmonary disease.

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Year:  1999        PMID： 10556166     DOI： 10.1164/ajrccm.160.supplement_1.9

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


  118 in total

1.  CX3CR1+ lung mononuclear phagocytes spatially confined to the interstitium produce TNF-α and IL-6 and promote cigarette smoke-induced emphysema.

Authors:  Zeyu Xiong; Adriana S Leme; Prabir Ray; Steven D Shapiro; Janet S Lee
Journal:  J Immunol       Date:  2011-01-28       Impact factor: 5.422

2.  Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression.

Authors:  Robert A Philibert; Rory A Sears; Linda S Powers; Emma Nash; Thomas Bair; Alicia K Gerke; Ihab Hassan; Christie P Thomas; Thomas J Gross; Martha M Monick
Journal:  J Leukoc Biol       Date:  2012-03-16       Impact factor: 4.962

3.  Emphysema mediated by lung overexpression of ADAM10.

Authors:  Hiroki Saitoh; Philip L Leopold; Ben-Gary Harvey; Timothy P O'Connor; Stefan Worgall; Neil R Hackett; Ronald G Crystal
Journal:  Clin Transl Sci       Date:  2009-02       Impact factor: 4.689

4.  Klotho Reduction in Alveolar Macrophages Contributes to Cigarette Smoke Extract-induced Inflammation in Chronic Obstructive Pulmonary Disease.

Authors:  Lingling Li; Yujie Wang; Wei Gao; Cheng Yuan; Sini Zhang; Hong Zhou; Mao Huang; Xin Yao
Journal:  J Biol Chem       Date:  2015-09-18       Impact factor: 5.157

5.  Enhancement of COPD biological networks using a web-based collaboration interface.

Authors:  Stephanie Boue; Brett Fields; Julia Hoeng; Jennifer Park; Manuel C Peitsch; Walter K Schlage; Marja Talikka; Ilona Binenbaum; Vladimir Bondarenko; Oleg V Bulgakov; Vera Cherkasova; Norberto Diaz-Diaz; Larisa Fedorova; Svetlana Guryanova; Julia Guzova; Galina Igorevna Koroleva; Elena Kozhemyakina; Rahul Kumar; Noa Lavid; Qingxian Lu; Swapna Menon; Yael Ouliel; Samantha C Peterson; Alexander Prokhorov; Edward Sanders; Sarah Schrier; Golan Schwaitzer Neta; Irina Shvydchenko; Aravind Tallam; Gema Villa-Fombuena; John Wu; Ilya Yudkevich; Mariya Zelikman
Journal:  F1000Res       Date:  2015-01-29

6.  Myeloid-specific Fos-related antigen-1 regulates cigarette smoke-induced lung inflammation, not emphysema, in mice.

Authors:  Michelle Vaz; Subbiah Rajasekaran; Haranatha R Potteti; Sekhar P Reddy
Journal:  Am J Respir Cell Mol Biol       Date:  2015-07       Impact factor: 6.914

7.  Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.

Authors:  Hongwei Yao; Jae-woong Hwang; Jorge Moscat; Maria T Diaz-Meco; Michael Leitges; Nandini Kishore; Xiong Li; Irfan Rahman
Journal:  J Biol Chem       Date:  2009-12-11       Impact factor: 5.157

8.  Regulation of expression of matrix metalloproteinase-9 by JNK in Raw 264.7 cells: presence of inhibitory factor(s) suppressing MMP-9 induction in serum and conditioned media.

Authors:  Yun Song Lee; Huong Thi Lan Tran; Quang Van Ta
Journal:  Exp Mol Med       Date:  2009-04-30       Impact factor: 8.718

9.  COPD is associated with a macrophage scavenger receptor-1 gene sequence variation.

Authors:  Jill A Ohar; Raymond F Hamilton; Siqun Zheng; Alireza Sadeghnejad; David A Sterling; Jianfeng Xu; Deborah A Meyers; Eugene R Bleecker; Andrij Holian
Journal:  Chest       Date:  2010-01-15       Impact factor: 9.410

10.  Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.

Authors:  Saravanan Rajendrasozhan; Sangwoon Chung; Isaac K Sundar; Hongwei Yao; Irfan Rahman
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2009-12-04       Impact factor: 5.464
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