Literature DB >> 10554532

[Molecular biology studies of a multicenter phase III study (SIC Study)].

T Zimmermann1, S Albrecht, G von Gagern.   

Abstract

Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.

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Year:  1999        PMID： 10554532     DOI： 10.1007/bf03042194

Source DB:  PubMed          Journal:  Med Klin (Munich)        ISSN： 0723-5003


  6 in total

1.  Role of NFkappaB in the mortality of sepsis.

Authors:  H Böhrer; F Qiu; T Zimmermann; Y Zhang; T Jllmer; D Männel; B W Böttiger; D M Stern; R Waldherr; H D Saeger; R Ziegler; A Bierhaus; E Martin; P P Nawroth
Journal:  J Clin Invest       Date:  1997-09-01       Impact factor: 14.808

Review 2.  Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases.

Authors:  P J Barnes; M Karin
Journal:  N Engl J Med       Date:  1997-04-10       Impact factor: 91.245

3.  Inhibition of NF-kappaB DNA binding and nitric oxide induction in human T cells and lung adenocarcinoma cells by selenite treatment.

Authors:  I Y Kim; T C Stadtman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-25       Impact factor: 11.205

4.  Binding of nuclear proteins to transcription regulatory elements in selenium deficiency.

Authors:  M J Christensen; N W Pusey
Journal:  Biochim Biophys Acta       Date:  1994-02-22

5.  Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-Rel/p65 heterodimers to a kappa B-like site.

Authors:  P A Oeth; G C Parry; C Kunsch; P Nantermet; C A Rosen; N Mackman
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

6.  A set of inducible genes expressed by activated human monocytic and endothelial cells contain kappa B-like sites that specifically bind c-Rel-p65 heterodimers.

Authors:  G C Parry; N Mackman
Journal:  J Biol Chem       Date:  1994-08-19       Impact factor: 5.157
  6 in total
  2 in total

Review 1.  Selenium supplementation for critically ill adults.

Authors:  Mikkel Allingstrup; Arash Afshari
Journal:  Cochrane Database Syst Rev       Date:  2015-07-27

2.  The β-SiC nanowires (~100 nm) induce apoptosis via oxidative stress in mouse osteoblastic cell line MC3T3-E1.

Authors:  Weili Xie; Qi Xie; Meishan Jin; Xiaoxiao Huang; Xiaodong Zhang; Zhengkai Shao; Guangwu Wen
Journal:  Biomed Res Int       Date:  2014-05-21       Impact factor: 3.411
  2 in total

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