Literature DB >> 1055407

Human epidermal growth factor: isolation and chemical and biological properties.

S Cohen, G Carpenter.   

Abstract

A polypeptide hormone has been isolated from human urine, human epidermal growth factor. It was assayed by its ability to compete with 125I-labeled mouse-derived epidermal growth factor in binding to human foreskin fibroblasts. The biological effects of the human polypeptide are similar to those previously described for the mouse hormone. These include the stimulation of the growth in vitro of human foreskin fibroblasts and corneal epithelial cells in organ culture, and the in vivo induction of precocious eyelid opening in the newborn mouse. The amino acid compositions of the two polypeptides differ, although certain similarities are present. The estimated molecular weight of the human polypeptide, 5300-5500, is slightly lower than that of the mouse hormone. Both polypeptides apparently compete for the same site on the cell membrane; and antibodies to the mouse polypeptide crossreact to some extent with the human hormone.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1055407      PMCID： PMC432524          DOI： 10.1073/pnas.72.4.1317

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  11 in total

1.  Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.

Authors:  S COHEN
Journal:  J Biol Chem       Date:  1962-05       Impact factor: 5.157

2.  The spectrophotometric determination of tyrosine and tryptophan in proteins.

Authors:  T W Goodwin; R A Morton
Journal:  Biochem J       Date:  1946       Impact factor: 3.857

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Specific volumes of proteins and the relationship to their amino acid contents.

Authors:  T L McMEEKIN; K MARSHALL
Journal:  Science       Date:  1952-08-08       Impact factor: 47.728

5.  Pituitary extracts and steroid hormones in the control of 3T3 cell growth.

Authors:  H A Armelin
Journal:  Proc Natl Acad Sci U S A       Date:  1973-09       Impact factor: 11.205

6.  Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin.

Authors:  M D Hollenberg; P Cuatrecasas
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

7.  Isolation and characterization of renin-like enzymes from mouse submaxillary glands.

Authors:  S Cohen; J M Taylor; K Murakami; A M Michelakis; T Inagami
Journal:  Biochemistry       Date:  1972-11-07       Impact factor: 3.162

8.  Proliferation of corneal epithelium induced by epidermal growth factor.

Authors:  C R Savage; S Cohen
Journal:  Exp Eye Res       Date:  1973-03       Impact factor: 3.467

9.  Epidermal growth factor. Location of disulfide bonds.

Authors:  C R Savage; J H Hash; S Cohen
Journal:  J Biol Chem       Date:  1973-11-25       Impact factor: 5.157

10.  A potential source of electrophoretic artifacts in polyacrylamide gels.

Authors:  W M Mitchell
Journal:  Biochim Biophys Acta       Date:  1967-09-19
View more
  101 in total

Review 1.  Polypeptide growth factors and the kidney: a developmental perspective.

Authors:  E D Avner
Journal:  Pediatr Nephrol       Date:  1990-07       Impact factor: 3.714

Review 2.  Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors.

Authors:  G Kovacs
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

Review 3.  The ERBB network: at last, cancer therapy meets systems biology.

Authors:  Yosef Yarden; Gur Pines
Journal:  Nat Rev Cancer       Date:  2012-07-12       Impact factor: 60.716

4.  Epidermal growth factor receptor inhibits colitis-associated cancer in mice.

Authors:  Philip E Dubé; Fang Yan; Shivesh Punit; Nandini Girish; Steven J McElroy; M Kay Washington; D Brent Polk
Journal:  J Clin Invest       Date:  2012-07-09       Impact factor: 14.808

5.  Immunohistochemical distribution of human epidermal growth factor in salivary gland tumours.

Authors:  M Mori; R Naito; K Tsukitani; Y Okada; T Hayashi; K Kato
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

6.  The source of urinary epidermal growth factor in humans.

Authors:  C Callegari; N P Laborde; G Buenaflor; C G Nascimento; J A Brasel; D A Fisher
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1988

7.  Decrease in epidermal growth factor receptor levels and production of material enhancing epidermal growth factor binding accompany the temperature-dependent changes from normal to transformed phenotype.

Authors:  P Guinivan; R L Ladda
Journal:  Proc Natl Acad Sci U S A       Date:  1979-07       Impact factor: 11.205

8.  Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

Authors:  P Gorden; J L Carpentier; S Cohen; L Orci
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

Review 9.  Neurotrophic factors for the investigation and treatment of movement disorders.

Authors:  Justo Garcia De Yébenes; Marina Sánchez; Maria Angeles Mena
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

10.  Thymoma: tumour type related to expression of epidermal growth factor (EGF), EGF-receptor, p53, v-erb B and ras p21.

Authors:  Y Hayashi; N Ishii; C Obayashi; K Jinnai; K Hanioka; Y Imai; H Itoh
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.