Literature DB >> 10552991

Cytopathic effect inhibition assay for determining the in-vitro susceptibility of herpes simplex virus to antiviral agents.

M Cotarelo1, P Catalán, C Sánchez-Carrillo, A Menasalvas, E Cercenado, A Tenorio, E Bouza.   

Abstract

We compare a rapid dilution method for the determination of antiviral susceptibility of herpes simplex virus (HSV) with the plaque reduction assay. A total of 84 HSV clinical isolates were studied by both methods to detect in-vitro resistance to acyclovir and foscarnet. The rapid method showed for the detection of HSV isolates resistant to acyclovir and foscarnet, a sensitivity of 96. 8% and 100% and specificity of 100% and 100%, respectively. This method provides an easy and accurate screening procedure for the susceptibility testing of HSV to antiviral agents.

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Year:  1999        PMID： 10552991     DOI： 10.1093/jac/44.5.705

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  10 in total

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Review 2.  Current and potential treatments for ubiquitous but neglected herpesvirus infections.

Authors:  Jonathan E Gable; Timothy M Acker; Charles S Craik
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3.  Novel N-benzenesulfonyl sophocarpinol derivatives as coxsackie B virus inhibitors.

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Journal:  ACS Med Chem Lett       Date:  2015-01-07       Impact factor: 4.345

4.  Novel Method Based on Real-Time Cell Analysis for Drug Susceptibility Testing of Herpes Simplex Virus and Human Cytomegalovirus.

Authors:  Jocelyne Piret; Nathalie Goyette; Guy Boivin
Journal:  J Clin Microbiol       Date:  2016-06-01       Impact factor: 5.948

5.  Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus.

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6.  Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus.

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7.  Isolation, characterization and acyclovir susceptibility of herpes simplex virus isolates among immunocompromised patients.

Authors:  Soumyabrata Nag; Mallika Sengupta; Soma Sarkar; Yogiraj Ray; Debprasad Chattopadhyay; Manideepa Sengupta
Journal:  Indian J Sex Transm Dis AIDS       Date:  2021-04-08

8.  Herpes simplex virus: isolation, cytopathological characterization and antiviral sensitivity.

Authors:  Carlos Nozawa; Lilian Yumi Hattori; Ligia Carla Faccin Galhardi; Nayara Lopes; Wesley Andrade Bomfim; Ligyana Korki de Cândido; Elbens Marcos Minoreli de Azevedo; Airton dos Santos Gon; Rosa Elisa Carvalho Linhares
Journal:  An Bras Dermatol       Date:  2014 May-Jun       Impact factor: 1.896

Review 9.  Natural and nature-inspired stilbenoids as antiviral agents.

Authors:  Luce M Mattio; Giorgia Catinella; Andrea Pinto; Sabrina Dallavalle
Journal:  Eur J Med Chem       Date:  2020-07-04       Impact factor: 6.514

Review 10.  Natural Products-Derived Chemicals: Breaking Barriers to Novel Anti-HSV Drug Development.

Authors:  Jakub Treml; Markéta Gazdová; Karel Šmejkal; Miroslava Šudomová; Peter Kubatka; Sherif T S Hassan
Journal:  Viruses       Date:  2020-01-29       Impact factor: 5.048
  10 in total

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