J S Shim1, D C Watts. 1. Biomaterials Science Unit, University of Manchester Dental School, UK. jfshim@fs1.den.man.ac.uk
Abstract
OBJECTIVES: To determine the effects on methylmethacrylate (MMA) monomer concentration of a second heat-cure cycle introduced for the purpose of processing a denture soft-liner. METHODS: Two denture-base resins (Lucitone199 and Trevalon; Dentsply International, York, PA, USA) were selected. Heat-cure cycles were S (73 degrees C/90 min + 100 degrees C/30 min); L (73 degrees C/9 h); SM (S + 100 degrees C/2 h); LM (L + 100 degrees C/2 h). Cycles SM and LM thus simulated the effect of a further, soft-liner, heat-cure cycle. Groups (n = 6) of the specimens of the denture-base were prepared in the form of thin polymer disks. Monomer was then obtained from the broken fragments of disks by acetone extraction. Concentrations of MMA monomer were determined by reversed-phase high performance liquid chromatography (HPLC). Two-way ANOVA and independent sample t-tests were used to compare the results. RESULTS: The cycle S, applied to Lucitone199, gave a mean concentration of 1.95 wt% MMA (SD 0.24). The cycle L gave the highest level of residual concentration of MMA monomer in both materials. Cycles SM and LM, applied to Trevalon and Lucitone199, gave significant reductions of residual concentration of MMA monomer (p < 0.05). SIGNIFICANCE: The HPLC method was suitable for determining the amount of residual monomer in the denture-base acrylic resin. A further (soft-liner) heat-cure cycle had a statistically significant effect on reducing residual monomer concentrations, and this may have an effect upon mechanical properties.
OBJECTIVES: To determine the effects on methylmethacrylate (MMA) monomer concentration of a second heat-cure cycle introduced for the purpose of processing a denture soft-liner. METHODS: Two denture-base resins (Lucitone199 and Trevalon; Dentsply International, York, PA, USA) were selected. Heat-cure cycles were S (73 degrees C/90 min + 100 degrees C/30 min); L (73 degrees C/9 h); SM (S + 100 degrees C/2 h); LM (L + 100 degrees C/2 h). Cycles SM and LM thus simulated the effect of a further, soft-liner, heat-cure cycle. Groups (n = 6) of the specimens of the denture-base were prepared in the form of thin polymer disks. Monomer was then obtained from the broken fragments of disks by acetone extraction. Concentrations of MMA monomer were determined by reversed-phase high performance liquid chromatography (HPLC). Two-way ANOVA and independent sample t-tests were used to compare the results. RESULTS: The cycle S, applied to Lucitone199, gave a mean concentration of 1.95 wt% MMA (SD 0.24). The cycle L gave the highest level of residual concentration of MMA monomer in both materials. Cycles SM and LM, applied to Trevalon and Lucitone199, gave significant reductions of residual concentration of MMA monomer (p < 0.05). SIGNIFICANCE: The HPLC method was suitable for determining the amount of residual monomer in the denture-base acrylic resin. A further (soft-liner) heat-cure cycle had a statistically significant effect on reducing residual monomer concentrations, and this may have an effect upon mechanical properties.