Literature DB >> 10549929

Bilateral anterior cingulotomy for chronic noncancer pain.

H A Wilkinson1, K M Davidson, R I Davidson.   

Abstract

OBJECTIVE: To document the value of bilateral anterior cingulotomy for patients with intractable chronic noncancer pain.
METHODS: Twenty-three patients who underwent 28 cingulotomies between 1979 and 1996 for chronic refractory pain were sent questionnaires regarding their subjective response to the surgery and its impact on their pain. Questions dealt with pre- and postoperative pain, ability to resume work or usual activity, medications, family and social interactions, and overall benefit of cingulotomy. Results were compared with long-term (average, 8 yr) clinical follow-up. In 13 patients, pain was predominantly caused by lumbar adhesive arachnoiditis or "failed back." The remainder had venous occlusive disease, ischemic bilateral leg pain, phantom leg pain, postoperative neck pain, or atypical facial pain.
RESULTS: Eighteen patients returned questionnaires; two patients died of unrelated causes. Seventy-two percent of patients reported improvement in their pain, 55% were no longer taking narcotics, 67% noted improvement in their family life, and 72% noted improvement in their social interactions. Fifty-six percent of patients reported that the cingulotomy was beneficial, and 28% returned to their usual activities or work. Thirty-nine percent of patients developed transient or well-controlled seizures. Five patients required a second cingulotomy, and one patient did well despite developing brain abscesses. Patient assessments corresponded closely with clinical assessments.
CONCLUSION: Bilateral anterior cingulotomy is safe for patients with refractory chronic pain. Seizures reported in this series were well controlled with medication. More than half of all respondents thought they had a positive outcome and that cingulotomy was beneficial to them. There were no deaths related to the procedure.

Entities:  

Mesh:

Year:  1999        PMID: 10549929     DOI: 10.1097/00006123-199911000-00023

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  18 in total

1.  Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function.

Authors:  D A Gusnard; E Akbudak; G L Shulman; M E Raichle
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-20       Impact factor: 11.205

Review 2.  Neurological diseases and pain.

Authors:  David Borsook
Journal:  Brain       Date:  2011-11-08       Impact factor: 13.501

Review 3.  Emotional processing in anterior cingulate and medial prefrontal cortex.

Authors:  Amit Etkin; Tobias Egner; Raffael Kalisch
Journal:  Trends Cogn Sci       Date:  2010-12-16       Impact factor: 20.229

4.  Lesion network localization of free will.

Authors:  R Ryan Darby; Juho Joutsa; Matthew J Burke; Michael D Fox
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-01       Impact factor: 11.205

Review 5.  The neural bases of obsessive-compulsive disorder in children and adults.

Authors:  Tiago V Maia; Rebecca E Cooney; Bradley S Peterson
Journal:  Dev Psychopathol       Date:  2008

Review 6.  Brodmann area 10: Collating, integrating and high level processing of nociception and pain.

Authors:  Ke Peng; Sarah C Steele; Lino Becerra; David Borsook
Journal:  Prog Neurobiol       Date:  2017-12-02       Impact factor: 11.685

Review 7.  Imaging pain: a potent means for investigating pain mechanisms in patients.

Authors:  M C Lee; I Tracey
Journal:  Br J Anaesth       Date:  2013-07       Impact factor: 9.166

Review 8.  Cerebral stimulation for the affective component of neuropathic pain.

Authors:  Andre G Machado; Kenneth B Baker; Ela Plow; Donald A Malone
Journal:  Neuromodulation       Date:  2012-10-24

Review 9.  Role of the Anterior Cingulate Cortex in Translational Pain Research.

Authors:  Xiao Xiao; Ming Ding; Yu-Qiu Zhang
Journal:  Neurosci Bull       Date:  2021-02-10       Impact factor: 5.203

10.  Electroacupuncture Ameliorates Chronic Inflammatory Pain-Related Anxiety by Activating PV Interneurons in the Anterior Cingulate Cortex.

Authors:  Fangbing Shao; Junfan Fang; Mengting Qiu; Sisi Wang; Danning Xi; Xiaomei Shao; Xiaofen He; Jianqiao Fang; Junying Du
Journal:  Front Neurosci       Date:  2021-07-05       Impact factor: 4.677

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.