Clinical and bacteriological profile of neonatal infections in metropolitan city based medical college nursery.

Out of 6319 live born babies, 310 (4.9%) with high risk factors and with clinical suspicion of sepsis were studied for incidence pattern of neonatal infections. Incidence of neonatal infection was 2.56% in normal weight babies and 8.42% in low birth weight babies. Total culture positivity was 48.38%. Klebsiella was the most frequent offender, followed by Staph aureus and Staph epidermidis. Majority of klebsiella species were sensitive to ceftriaxone (86%), amikacin (84%) and ceftazidime (80%). Ceftriaxone was effective against Staph aureus (95%) and Staph epidermidis (95%). Overall fatality was 17.1%, distinctly higher in low birth weight group (22.06%) than normal weight group (6.18%).