Literature DB >> 1054848

A very rapid effect of androgen on initiation of protein synthesis in prostate.

T Liang, S Liao.   

Abstract

The initiation of protein synthesis by ribosomal particles of rat ventral prostate was studied by measuring ribosomal binding of an initiator (35-S)methionyl-tRNAf. The binding activity is dependent on ribosomes, GTP, and a prostate cytosol protein fraction. The 40S but not the 60S ribosomal subunit particles are active. The cytosol activity decreases rapidly within one hour after the rat is castrated. This loss is prevented by an intraperitoneal injection of 17beta-hydroxy-5-alpha-androstan-3-one (5-alpha-dihydrotestosterone). The cytosol activity can be stimulated almost immediately (within 10 min) after an intravenous injection of low dose (15 mug per rat) of 5-alpha-dihydrotestosterone into the castrated rat.

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Year:  1975        PMID： 1054848      PMCID： PMC432384          DOI： 10.1073/pnas.72.2.706

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  An effect of testosterone on amino acid incorporation by prostatic ribonucleoprotein particles.

Authors:  S LIAO; H G WILLIAMS-ASHMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1962-11-15       Impact factor: 11.205

2.  Experiments on hemoglobin biosynthesis.

Authors:  G VON EHRENSTEIN; F LIPMANN
Journal:  Proc Natl Acad Sci U S A       Date:  1961-07-15       Impact factor: 11.205

3.  Protein synthesis initiation in eukaryotes. Characterization of ribosomal factors from mouse fibroblasts.

Authors:  D H Levin; D Kyner; G Acs
Journal:  J Biol Chem       Date:  1973-09-25       Impact factor: 5.157

4.  Association of the uterine 17beta-estradiol-receptor complex with ribonucleoprotein in vitro and in vivo.

Authors:  T Liang; S Liao
Journal:  J Biol Chem       Date:  1974-08-10       Impact factor: 5.157

5.  Ribonucleoprotein binding of steroid-"receptor" complexes.

Authors:  S Liao; T Liang; J L Tymoczko
Journal:  Nat New Biol       Date:  1973-02-14

6.  Initiation of eukaryotic protein synthesis: (Met-tRNA f -40S ribosome) initiation complex catalysed by purified initiation factors in the absence of mRNA.

Authors:  M H Schreier; T Staehelin
Journal:  Nat New Biol       Date:  1973-03-14

7.  Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit.

Authors:  C Darnbrough; S Legon; T Hunt; R J Jackson
Journal:  J Mol Biol       Date:  1973-05-25       Impact factor: 5.469

8.  Initiation of globin synthesis. Preparation and use of reticulocyte ribosomes retaining initiation region messenger ribonucleic acid fragments.

Authors:  R G Crystal; A W Nienhuis; N A Elson; W F Anderson
Journal:  J Biol Chem       Date:  1972-09-10       Impact factor: 5.157

9.  Roles of methionine transfer RNA's in protein synthesis in rabbit reticulocytes.

Authors:  N K Gupta; N K Chatterjee; K K Bose; S Bhaduri; A Chung
Journal:  J Mol Biol       Date:  1970-11-28       Impact factor: 5.469

10.  Simplicity of mammalian regulatory systems inferred by single gene determination of sex phenotypes.

Authors:  S Ono
Journal:  Nature       Date:  1971-11-19       Impact factor: 49.962
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  10 in total

Review 1.  Prostate gland: structure, functions and regulation.

Authors:  V L Kumar; P K Majumder
Journal:  Int Urol Nephrol       Date:  1995       Impact factor: 2.370

2.  The relationship between adrogen receptors and the hormonally controlled responses of rat ventral prostate.

Authors:  E Van Doorn; S Craven; N Bruchovsky
Journal:  Biochem J       Date:  1976-10-15       Impact factor: 3.857

3.  Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.

Authors:  Anna Pluciennik; Yuhong Liu; Elana Molotsky; Gregory B Marsh; Bedri Ranxhi; Frederick J Arnold; Sophie St-Cyr; Beverly Davidson; Naemeh Pourshafie; Andrew P Lieberman; Wei Gu; Sokol V Todi; Diane E Merry
Journal:  J Clin Invest       Date:  2021-01-04       Impact factor: 14.808

4.  Research Resource: Androgen Receptor Activity Is Regulated Through the Mobilization of Cell Surface Receptor Networks.

Authors:  Jordy J Hsiao; Brandon H Ng; Melinda M Smits; Harryl D Martinez; Rohini J Jasavala; Izumi V Hinkson; Damian Fermin; Jimmy K Eng; Alexey I Nesvizhskii; Michael E Wright
Journal:  Mol Endocrinol       Date:  2015-07-16

5.  Auxin-induced Changes in the Incorporation of H-Amino Acids into Soybean Ribosomal Proteins.

Authors:  R L Travis; J L Key
Journal:  Plant Physiol       Date:  1976-06       Impact factor: 8.340

6.  Estradiol receptor of calf uterus: interactions with heparin-agarose and purification.

Authors:  A M Molinari; N Medici; B Moncharmont; G A Puca
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

7.  Studies on the mode of oestrogenic inhibition of hepatic synthesis of alpha2u-globulin and its corresponding messenger ribonucleic acid in rat liver.

Authors:  A K Roy; D J Dowbenko; M J Schiop
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

8.  Androgen signaling promotes translation of TMEFF2 in prostate cancer cells via phosphorylation of the α subunit of the translation initiation factor 2.

Authors:  Ryan F Overcash; Vesna A Chappell; Thomas Green; Christopher B Geyer; Adam S Asch; Maria J Ruiz-Echevarría
Journal:  PLoS One       Date:  2013-02-06       Impact factor: 3.240

9.  Glucocorticoid regulation of amino acid transport in anucleate rat hepatoma (HTC) cells.

Authors:  R A McDonald; T D Gelehrter
Journal:  J Cell Biol       Date:  1981-03       Impact factor: 10.539

10.  Discovery Proteomics Identifies a Molecular Link between the Coatomer Protein Complex I and Androgen Receptor-dependent Transcription.

Authors:  Jordy J Hsiao; Melinda M Smits; Brandon H Ng; Jinhee Lee; Michael E Wright
Journal:  J Biol Chem       Date:  2016-06-30       Impact factor: 5.157
  10 in total

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