Literature DB >> 10545983

Prion replication-once again blaming the dendritic cell.

M S Sy, P Gambetti.   

Abstract

The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308-1312).

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Year:  1999        PMID: 10545983     DOI: 10.1038/15186

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  2 in total

1.  Peripheral prion pursuit.

Authors:  A Aguzzi
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

2.  Test for detection of disease-associated prion aggregate in the blood of infected but asymptomatic animals.

Authors:  Binggong Chang; Xin Cheng; Shaoman Yin; Tao Pan; Hongtao Zhang; Poki Wong; Shin-Chung Kang; Fan Xiao; Huimin Yan; Chaoyang Li; Lisa L Wolfe; Michael W Miller; Thomas Wisniewski; Mark I Greene; Man-Sun Sy
Journal:  Clin Vaccine Immunol       Date:  2006-11-01
  2 in total

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