Literature DB >> 10544952

Expression of 5-HT2A and 5-HT1B receptor mRNA in blood vessels.

S Kato1, H Kumamoto, M Hirano, H Akiyama, N Kaneko.   

Abstract

Expression of two subtypes of 5-hydroxytryptamine (5-HT) receptors, 5-HT1B and 5-HT2A, was investigated in normal rat arteries (abdominal aorta) and veins (inferior vena cava) by the quantitative reverse transcription-polymerase chain reaction (RT-PCR). The arterial 5-HT2A receptor mRNA level in artery was 25-fold (p < 0.01) higher than the venous level, and the arterial 5-HT1B receptor mRNA level was at least 7000-fold (p < 0.005) higher the venous level.

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Year:  1999        PMID: 10544952     DOI: 10.1023/a:1006999031932

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN: 0300-8177            Impact factor:   3.396


  7 in total

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Authors:  H Akiyama; S Kanai; M Hirano; Y Kumei; H Shimokawa; H Katano; E Hara; S Song; C Mukai; S Nagaoka
Journal:  J Biotechnol       Date:  1996-06-27       Impact factor: 3.307

Review 2.  Vascular receptors for 5-hydroxytryptamine: distribution, function and classification.

Authors:  G R Martin
Journal:  Pharmacol Ther       Date:  1994       Impact factor: 12.310

3.  Platelet-mediated vascular contractions: inhibition of the serotonergic component by ketanserin.

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Review 4.  International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

Authors:  D Hoyer; D E Clarke; J R Fozard; P R Hartig; G R Martin; E J Mylecharane; P R Saxena; P P Humphrey
Journal:  Pharmacol Rev       Date:  1994-06       Impact factor: 25.468

5.  Pharmacological profile of the receptors that mediate external carotid vasoconstriction by 5-HT in vagosympathectomized dogs.

Authors:  C M Villalón; E Ramírez-San Juan; C Castillo; E Castillo; F J López-Muñoz; J A Terrón
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

6.  Expression of serotonin receptor mRNAs in blood vessels.

Authors:  C Ullmer; K Schmuck; H O Kalkman; H Lübbert
Journal:  FEBS Lett       Date:  1995-08-21       Impact factor: 4.124

7.  5-Hydroxytryptamine-induced synovial plasma extravasation is mediated via 5-hydroxytryptamine2A receptors on sympathetic efferent terminals.

Authors:  P A Pierce; G X Xie; S J Peroutka; P G Green; J D Levine
Journal:  J Pharmacol Exp Ther       Date:  1995-10       Impact factor: 4.030

  7 in total
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Journal:  J Anim Sci       Date:  2018-04-14       Impact factor: 3.159

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  3 in total

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