| Literature DB >> 10544259 |
Abstract
In the living cellular environment, DNAs exist in a compact state in the presence of a polyamine, such as spermidine. We found that the hydrolysis of ATP into ADP induces the folding of elongated DNAs, by the single-chain observation of individual T4 DNA molecules. This result is discussed in relation to the possible role of ATP as a regulatory factor in genetic activity, in addition to its well-established role as an energy source.Entities:
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Year: 1999 PMID： 10544259 DOI： 10.1016/s0014-5793(99)01368-x
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124