| Literature DB >> 10543676 |
Y C Ong, H B Wong, G Adaikan, E L Yong.
Abstract
We report a 46,XY infant with an M807T mutation in his androgen receptor that abrogated cellular responses to testosterone, but not to dihydrotestosterone (DHT), resulting in ambiguous genitalia. Treatment with a topical DHT gel restored male genital development allowing the infant to be reared in accordance with his chromosomal sex.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10543676 DOI： 10.1016/s0140-6736(99)03205-5
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321