Literature DB >> 10543550

Off or on bypass: what is the safety threshold?

A L Iacò1, M Contini, G Teodori, M Di Mauro, G Di Giammarco, G Vitolla, T Iovino, A M Calafiore.   

Abstract

BACKGROUND: To identify the technical profile of the patients operated on without cardiopulmonary bypass (CPB) and the benefit of the procedure.
METHODS: From May 21, 1997, to December 31, 1998, 785 patients had coronary artery bypass grafting through a median sternotomy (group A: 472 without CPB; group B: 290 with CPB; group C: 23 converted). Technical aspects, mortality rate, cerebrovascular accident (CVA) incidence (crude and risk-adjusted), and incidence of major complications were recorded.
RESULTS: Patients without CPB had mainly one to three grafts and one- or two-vessel disease. Multiple arterial grafting was not a limit, whereas sequential grafting was. Group A had lower complications rates, shorter intensive care unit and postoperative in hospital stays, and lower transfusion rates. Mortality rates and CVA incidence (crude and risk-adjusted) were similar in both groups and in each subgroup considered. In group A, a lower complications rate was present in some patients (aged greater than 70 years, female, with unstable angina). Group C showed higher mortality and complications rates. Failure of revascularization showed no difference between groups.
CONCLUSIONS: Primary endpoints are not affected by the surgical strategy, whereas some of the secondary endpoints are. However, patients in group A experienced fewer complications. Both techniques can give satisfying results and must be applied according to the surgeon's preference.

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Mesh:

Year:  1999        PMID: 10543550     DOI: 10.1016/s0003-4975(99)00957-1

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  6 in total

Review 1.  Improving the cost-effectiveness of coronary artery bypass grafting surgery. Better clinical research or simply better management?

Authors:  D R Miranda
Journal:  Intensive Care Med       Date:  2001-03       Impact factor: 17.440

2.  Effects of half-dose aprotinin in off-pump coronary artery bypass grafting.

Authors:  Minxin Wei; Kaitao Jian; Zhipeng Guo; Peijun Li; Jiange Han; Zhong Cai; Matti Tarkka
Journal:  World J Surg       Date:  2006-06       Impact factor: 3.352

Review 3.  Off-pump coronary artery bypass graft surgery is standard of care: where do you stand?

Authors:  Jean-Francois Légaré; Gregory Hirsch
Journal:  Can J Cardiol       Date:  2006-11       Impact factor: 5.223

4.  Activation of coagulation and fibrinolysis during coronary artery bypass grafting: a comparison between on-pump and off-pump techniques.

Authors:  Shreosee Roy; Kaushik Saha; Krishnendu Mukherjee; Santanu Dutta; Debasis Mukhopadhyay; Indranil Das; Gargi Raychaudhuri
Journal:  Indian J Hematol Blood Transfus       Date:  2013-04-26       Impact factor: 0.900

5.  Off-pump versus on-pump coronary artery bypass grafting in acute coronary syndrome: a clinical analysis.

Authors:  Kaan Kaya; Raif Cavolli; Alpaslan Telli; Mehmet Fazil Tolga Soyal; Alp Aslan; Gökhan Gokaslan; Sahin Mursel; Refik Tasoz
Journal:  J Cardiothorac Surg       Date:  2010-04-27       Impact factor: 1.637

Review 6.  Myocardial revascularization without extracorporeal circulation; Why hasn't it convinced yet?

Authors:  Efstratios Apostolakis; Nikolaos A Papakonstantinou; Ioanna Koniari
Journal:  Ann Card Anaesth       Date:  2017 Apr-Jun
  6 in total

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