Literature DB >> 10542396

Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression.

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Abstract

It is hoped that this review will give the reader a taste of some of the mechanisms used by the glucocorticoid receptor to repress gene function. These mechanisms include direct binding to DNA, antagonism of other transcription factor families and sequestration of necessary cofactors. Each of these mechanisms, and others, are discussed.

Entities:  

Year:  1999        PMID： 10542396     DOI： 10.1016/s1043-2760(99)00186-1

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  38 in total

Review 1.  Clinical pharmacology of inflammatory bowel disease therapies.

Authors:  W J Sandborn; W A Faubion
Journal:  Curr Gastroenterol Rep       Date:  2000-12

2.  IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response.

Authors:  Maureen B Josephson; Junfang Jiao; Shuyun Xu; Aihua Hu; Chinmay Paranjape; Judith S Grunstein; Yael Grumbach; Gustavo Nino; Portia A Kreiger; Joseph McDonough; Michael M Grunstein
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2012-07-06       Impact factor: 5.464

3.  Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia.

Authors:  Jason R Schwartz; Purvaba J Sarvaiya; Wayne V Vedeckis
Journal:  Mol Cell Endocrinol       Date:  2010-02-17       Impact factor: 4.102

4.  Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex.

Authors:  U S Sandau; R J Handa
Journal:  Neuroscience       Date:  2006-11-15       Impact factor: 3.590

5.  False responses of Renilla luciferase reporter control to nuclear receptor TR4.

Authors:  Dongyun Zhang; Sam S Atlasi; Krishna K Patel; Zihao Zhuang; Anthony P Heaney
Journal:  Mol Cell Biochem       Date:  2017-02-16       Impact factor: 3.396

6.  Discovery of GW870086: a potent anti-inflammatory steroid with a unique pharmacological profile.

Authors:  I J Uings; D Needham; J Matthews; M Haase; R Austin; D Angell; K Leavens; J Holt; K Biggadike; S N Farrow
Journal:  Br J Pharmacol       Date:  2013-07       Impact factor: 8.739

Review 7.  Dissection of glucocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis by gene targeting in mice.

Authors:  Gloria Laryea; Lisa Muglia; Melinda Arnett; Louis J Muglia
Journal:  Front Neuroendocrinol       Date:  2014-09-27       Impact factor: 8.606

8.  Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells.

Authors:  M Rockwell Parker; Dianna Feng; Brianna Chamuris; Robert F Margolskee
Journal:  Neurosci Lett       Date:  2014-05-06       Impact factor: 3.046

9.  Modulation of transcription parameters in glucocorticoid receptor-mediated repression.

Authors:  Yunguang Sun; Yong-Guang Tao; Benjamin L Kagan; Yuangzheng He; S Stoney Simons
Journal:  Mol Cell Endocrinol       Date:  2008-05-21       Impact factor: 4.102

Review 10.  What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.

Authors:  S Stoney Simons
Journal:  Bioessays       Date:  2008-08       Impact factor: 4.345
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