Literature DB >> 10542310

Cloning and expression profile of human inorganic pyrophosphatase.

T A Fairchild1, G Patejunas.   

Abstract

We have cloned a 1.23 kb cDNA from a human heart library which encodes a 32 kDa protein that is 94% identical to bovine inorganic pyrophosphatase. The protein contains an aspartate-rich signature sequence that was previously identified in yeast and prokaryotic pyrophosphatases. Our clone detects a single band on Northern blots and is expressed at modest levels in all tissues examined. The cDNA shows linkage to markers on the long arm of chromosome 10.

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Year:  1999        PMID: 10542310     DOI: 10.1016/s0167-4781(99)00175-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  6 in total

1.  Clinical significance and functional validation of inorganic pyrophosphatase in diffuse large B cell lymphoma in humans.

Authors:  Limei Li; Dehong Luo; Arong Jin
Journal:  Cytotechnology       Date:  2017-12-12       Impact factor: 2.058

2.  Pyrophosphatase overexpression is associated with cell migration, invasion, and poor prognosis in gastric cancer.

Authors:  Sang-Ho Jeong; Gyung Hyuck Ko; Young Hyun Cho; Young-Joon Lee; Bok-Im Cho; Woo-Song Ha; Sang-Kyung Choi; Jae Won Kim; Chang Won Lee; Yoon Seok Heo; Seok Hwan Shin; Jiyun Yoo; Soon-Chan Hong
Journal:  Tumour Biol       Date:  2012-07-14

3.  Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.

Authors:  Martin Schlee; Tanja Krug; Olivier Gires; Reinhard Zeidler; Wolfgang Hammerschmidt; Reinhard Mailhammer; Gerhard Laux; Guido Sauer; Josip Lovric; Georg W Bornkamm
Journal:  J Virol       Date:  2004-04       Impact factor: 5.103

4.  Identification of the inorganic pyrophosphate metabolizing, ATP substituting pathway in mammalian spermatozoa.

Authors:  Young-Joo Yi; Miriam Sutovsky; Chelsey Kennedy; Peter Sutovsky
Journal:  PLoS One       Date:  2012-04-02       Impact factor: 3.240

5.  Clinical significance and functional validation of PPA1 in various tumors.

Authors:  Dehong Luo; Guanwen Wang; Wenzhi Shen; Shuangtao Zhao; Wei Zhou; Lin Wan; Liying Yuan; Shuang Yang; Rong Xiang
Journal:  Cancer Med       Date:  2016-09-26       Impact factor: 4.452

6.  Silencing PPA1 inhibits human epithelial ovarian cancer metastasis by suppressing the Wnt/β-catenin signaling pathway.

Authors:  Haiying Niu; Wei Zhou; Yingxi Xu; Zhiqi Yin; Wenzhi Shen; Zhen Ye; Yanhua Liu; Yanan Chen; Shuang Yang; Rong Xiang; Lina Wang; Pengpeng Qu
Journal:  Oncotarget       Date:  2017-07-18
  6 in total

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