| Literature DB >> 10542084 |
H S Chan1.
Abstract
A new computational approach optimizes searches for reduced protein folding alphabets that use fewer than 20 types of amino acids. The predicted optimal five-letter alphabet happens to be in agreement with the suggestive results of a recent experiment, but whether highly reduced alphabets are sufficient for truly protein-like properties remains an open experimental question.Mesh:
Substances:
Year: 1999 PMID: 10542084 DOI: 10.1038/14876
Source DB: PubMed Journal: Nat Struct Biol ISSN: 1072-8368