Literature DB >> 10541105

Evaluation of dynamic gadolinium-enhanced breath-hold MR angiography in the diagnosis of renal artery stenosis.

M J Thornton1, F Thornton, J O'Callaghan, J C Varghese, E O'Brien, J Walshe, M J Lee.   

Abstract

OBJECTIVE: The aim of our study was to evaluate a three-dimensional gadolinium-enhanced breath-hold MR angiography sequence using standard MR gradients in detecting renal artery stenosis. SUBJECTS AND METHODS: Forty-two patients referred for angiography for suspected renal artery stenosis underwent both conventional digital subtraction angiography (DSA) and MR angiography. MR angiography was performed on a 1.5-T scanner with standard gradients. A fast multiplanar spoiled gradient-echo sequence was used with the following parameters: TR/TE, 10.3/1.9; flip angle, 45 degrees; field of view, 36 x 32 cm; matrix size, 256 x 128; one excitation; volume thickness, 70 mm; and partitions, 28. Gadolinium was administered IV as a dynamic bolus of 30-40 ml. Conventional and MR angiographic images were interpreted by two radiologists in consensus.
RESULTS: DSA revealed 87 renal arteries, of which 79 were in 35 patients with native kidneys and eight arteries were in seven patients with transplanted kidneys. Gadolinium-enhanced MR angiography showed 85 (98%) of 87 renal arteries. Seventeen patients had 20 significant (>50% stenosis) renal artery stenoses and five patients had five occluded renal arteries revealed by DSA. MR angiography revealed 85 renal arteries (98%), 20 stenoses (100%), and five occlusions (100%). Gadolinium-enhanced MR angiography led to one false-positive interpretation for renal artery stenosis and no false-negative interpretations. Thus, the sensitivity, specificity, and accuracy of MR angiography for renal artery stenosis were 100%, 98%, and 99%, respectively.
CONCLUSION: The MR angiography pulse sequence we used was an effective and reliable technique for the diagnosis of renal artery stenosis. The sequence can be performed on widely available MR equipment that does not require fast gradient hardware.

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Year:  1999        PMID: 10541105     DOI: 10.2214/ajr.173.5.10541105

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  4 in total

1.  Contrast-bolus MR angiography of the transplanted kidney with a low-field (0.5-T) scanner: diagnostic accuracy, sensitivity and specificity of images and reconstructions in the evaluation of vascular complications.

Authors:  A Stecco; P Oronzo; F Armienti; C Borraccino; R Fossaceca; L Canalis; A Carriero
Journal:  Radiol Med       Date:  2007-10-21       Impact factor: 3.469

2.  The current state of endovascular therapy in the evaluation and management of renovascular disease.

Authors:  Praveen R Anchala; Scott A Resnick
Journal:  Semin Intervent Radiol       Date:  2009-12       Impact factor: 1.513

3.  Comparing Diagnostic Techniques of Magnetic Resonance Angiography (MRA) and Doppler Ultrasonography in Determining Severity of Renal Artery Stenosis.

Authors:  Mohammad Hashemi Jazi; Mahfar Arasteh; Hamid Shamsolketabi; Aliakbar Tavassoli; Peyman Nilforoush; Mojgan Gharipour
Journal:  ARYA Atheroscler       Date:  2011

4.  How to measure renal artery stenosis--a retrospective comparison of morphological measurement approaches in relation to hemodynamic significance.

Authors:  Malin Andersson; Karl Jägervall; Per Eriksson; Anders Persson; Göran Granerus; Chunliang Wang; Örjan Smedby
Journal:  BMC Med Imaging       Date:  2015-10-12       Impact factor: 1.930

  4 in total

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