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Literature DB >> 1054098

Friend leukemia: rapid development of erythropoietin-independent hematopoietic precursors.

Abstract

Infection of mice with the polycythemia-inducing strain of Friend leukemia virus caused a rapid emergence of new erythroid precursor cells. These cells which, in the absence of erythropoietin, proliferated in vitro to form colonies and even differnetiated, quickly out-numbered the usual erythropoietin-dependent hematopoietic elements in bone marrow and spleen. Ultimately, the marrow and spleen were probably totally repopulated with this erythropoietin-independent cell.

Entities: Disease Gene Species

Mesh：

Substances：
Erythropoietin

Year: 1975 PMID： 1054098 DOI： 10.1093/jnci/54.1.265

Source DB: PubMed Journal: J Natl Cancer Inst ISSN： 0027-8874 Impact factor: 13.506

Keyword Cloud
Cited

25 in total

1. Clonal analysis of the late stages of erythroleukemia induced by two distinct strains of Friend leukemia virus.

Authors: D Mager; M E MacDonald; I B Robson; T W Mak; A Bernstein
Journal: Mol Cell Biol Date: 1981-08 Impact factor: 4.272

2. Erythroid stem cells in Rauscher virusinfected mice.

Authors: U Opitz; H J Seidel; I S Rich
Journal: Blut Date: 1977-07-20

3. Both the polycythemia- and anemia-inducing strains of Friend spleen focus-forming virus induce constitutive activation of the Raf-1/mitogen-activated protein kinase signal transduction pathway.

Authors: K W Muszynski; T Ohashi; C Hanson; S K Ruscetti
Journal: J Virol Date: 1998-02 Impact factor: 5.103

4. Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth.

Authors: S W Chung; L Wolff; S K Ruscetti
Journal: Proc Natl Acad Sci U S A Date: 1989-10 Impact factor: 11.205

5. Sequences responsible for the altered erythropoietin responsiveness in spleen focus-forming virus strain SFFVP-infected cells are localized to a 678-base-pair region at the 3' end of the envelope gene.

Authors: S W Chung; L Wolff; S Ruscetti
Journal: J Virol Date: 1987-05 Impact factor: 5.103

10. Variations in erythropoiesis throughout a lifetime. Studies in a high-leukaemic mouse strain, the AKR/O strain, and a non-leukaemic strain, the WLO strain.

Authors: M Hellebostad; T Sanengen; S Halvorsen
Journal: Blut Date: 1990-12

Friend leukemia: rapid development of erythropoietin-independent hematopoietic precursors.

1. Clonal analysis of the late stages of erythroleukemia induced by two distinct strains of Friend leukemia virus.

2. Erythroid stem cells in Rauscher virusinfected mice.

3. Both the polycythemia- and anemia-inducing strains of Friend spleen focus-forming virus induce constitutive activation of the Raf-1/mitogen-activated protein kinase signal transduction pathway.

4. Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth.

5. Sequences responsible for the altered erythropoietin responsiveness in spleen focus-forming virus strain SFFVP-infected cells are localized to a 678-base-pair region at the 3' end of the envelope gene.

6. Effect of actinomycin D and busulphan on stem cells in normal and Friend virus infected mice.

7. Comparison of the biological effects of anemia inducing and polycythemia inducing Friend virus complex.

8. Production of erythropoietin-like activity by a murine erythroleukemia cell line.

9. Effects of ribavirin on the development of the Friend leukemia.

10. Variations in erythropoiesis throughout a lifetime. Studies in a high-leukaemic mouse strain, the AKR/O strain, and a non-leukaemic strain, the WLO strain.