M Gelman1, D W Chakeres, H B Newton. 1. Department of Radiology, Ohio State University Medical Center, Columbus 43210, USA.
Abstract
PURPOSE: To evaluate the rate of complications associated with diagnostic cerebral angiography accompanied by intraarterial chemotherapy for the treatment of primary and metastatic brain tumors. MATERIALS AND METHODS: Three hundred ninety-two consecutive transfemoral cerebral angiographic procedures accompanied by intraarterial chemotherapy were performed in 48 patients (28 men, 20 women), and complications were evaluated. RESULTS: The most common local complications were groin hematomas, which occurred in 10 (2.6%) of the 392 procedures and none of which required therapy. Two carotid arterial dissections (0.5%) were reported in two patients who were asymptomatic and did not require further treatment. Both improved at follow-up examinations. Only one patient required surgery for a delayed popliteal embolus. Systemic transient complications occurred five times (1.3%). There were seven (1.8%) transient neurologic events, which were paresis and visual disturbances. Six (1.5%) transient seizure events were recorded. There were no permanent neurologic complications. CONCLUSION: Intraarterial chemotherapy for brain tumors is a safe procedure with a low complication rate.
PURPOSE: To evaluate the rate of complications associated with diagnostic cerebral angiography accompanied by intraarterial chemotherapy for the treatment of primary and metastatic brain tumors. MATERIALS AND METHODS: Three hundred ninety-two consecutive transfemoral cerebral angiographic procedures accompanied by intraarterial chemotherapy were performed in 48 patients (28 men, 20 women), and complications were evaluated. RESULTS: The most common local complications were groin hematomas, which occurred in 10 (2.6%) of the 392 procedures and none of which required therapy. Two carotid arterial dissections (0.5%) were reported in two patients who were asymptomatic and did not require further treatment. Both improved at follow-up examinations. Only one patient required surgery for a delayed popliteal embolus. Systemic transient complications occurred five times (1.3%). There were seven (1.8%) transient neurologic events, which were paresis and visual disturbances. Six (1.5%) transient seizure events were recorded. There were no permanent neurologic complications. CONCLUSION: Intraarterial chemotherapy for brain tumors is a safe procedure with a low complication rate.
Authors: Ronit Agid; Rina Rubinstein; Tali Siegal; Hava Lester; Felix Bokstein; Roland Chisin; John M Gomori Journal: AJNR Am J Neuroradiol Date: 2002 Nov-Dec Impact factor: 3.825
Authors: Herbert B Newton; Mary A Slivka; Carol Volpi; Eric C Bourekas; Gregory A Christoforidis; Melissa A Baujan; Wayne Slone; Donald W Chakeres Journal: J Neurooncol Date: 2003-01 Impact factor: 4.130
Authors: E Osztie; P Várallyay; N D Doolittle; C Lacy; G Jones; H S Nickolson; E A Neuwelt Journal: AJNR Am J Neuroradiol Date: 2001-05 Impact factor: 3.825
Authors: Herbert B Newton; Mary Ann Slivka; Carol L Stevens; Eric C Bourekas; Gregory A Christoforidis; Melissa A Baujan; Donald W Chakeres Journal: J Neurooncol Date: 2002-01 Impact factor: 4.130