| Literature DB >> 10540432 |
.
Abstract
Formation of the C11-C1' bond through application of Barton's radical decarboxylation and quinone addition is the cornerstone of a new convergent and concise synthesis of the marine metabolites avarol (1) and avarone (2; see scheme), for which antimitotic, antileukemic, and antiviral effects have been reported.Entities:
Year: 1999 PMID: 10540432 DOI: 10.1002/(sici)1521-3773(19991018)38:20<3089::aid-anie3089>3.0.co;2-w
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336