| Literature DB >> 10540403 |
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Abstract
Both oxidized and reduced glutathione (gamma-L-Glu-L-Cys-Gly) react with the anticancer complex [Pt(en)Cl(2)] to form the bicyclic complex illustrated (en=ethylenediamine). This unprecedented structure, which was determined from extensive NMR experiments, contains a ten-membered macrochelate ring.Entities:
Year: 1999 PMID： 10540403 DOI： 10.1002/(sici)1521-3773(19991004)38:19<2949::aid-anie2949>3.0.co;2-q
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336