Literature DB >> 10535608

TNF-alpha and chronic fatigue syndrome.

R B Moss1, A Mercandetti, A Vojdani.   

Abstract

Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results suggest a significant increase serum TNF-alpha in patients with CFS (P<0.0001) compared to non-CFS controls. This study supports the further examination of the role of proinflammatory mediators in CFS. Furthermore, the clinical testing of TNF-alpha blockers and other antiinflammatory agents for the treatment of this disease is warranted.

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Year:  1999        PMID： 10535608     DOI： 10.1023/a:1020595709352

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  11 in total

1.  Markers of inflammation and immune activation in chronic fatigue and chronic fatigue syndrome.

Authors:  D Buchwald; M H Wener; T Pearlman; P Kith
Journal:  J Rheumatol       Date:  1997-02       Impact factor: 4.666

2.  Cytokine production by adherent and non-adherent mononuclear cells in chronic fatigue syndrome.

Authors:  S Gupta; S Aggarwal; D See; A Starr
Journal:  J Psychiatr Res       Date:  1997 Jan-Feb       Impact factor: 4.791

3.  CD4 T lymphocytes from patients with chronic fatigue syndrome have decreased interferon-gamma production and increased sensitivity to dexamethasone.

Authors:  J Visser; B Blauw; B Hinloopen; E Brommer; E R de Kloet; C Kluft; L Nagelkerken
Journal:  J Infect Dis       Date:  1998-02       Impact factor: 5.226

4.  Interleukin-1 beta, interleukin-1 receptor antagonist, and soluble interleukin-1 receptor type II secretion in chronic fatigue syndrome.

Authors:  J G Cannon; J B Angel; L W Abad; E Vannier; M D Mileno; L Fagioli; S M Wolff; A L Komaroff
Journal:  J Clin Immunol       Date:  1997-05       Impact factor: 8.317

5.  Elevation of bioactive transforming growth factor-beta in serum from patients with chronic fatigue syndrome.

Authors:  A L Bennett; C C Chao; S Hu; D Buchwald; L R Fagioli; P H Schur; P K Peterson; A L Komaroff
Journal:  J Clin Immunol       Date:  1997-03       Impact factor: 8.317

6.  A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate.

Authors:  M E Weinblatt; J M Kremer; A D Bankhurst; K J Bulpitt; R M Fleischmann; R I Fox; C G Jackson; M Lange; D J Burge
Journal:  N Engl J Med       Date:  1999-01-28       Impact factor: 91.245

7.  Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome.

Authors:  R J Suhadolnik; N L Reichenbach; P Hitzges; R W Sobol; D L Peterson; B Henry; D V Ablashi; W E Müller; H C Schröder; W A Carter
Journal:  Clin Infect Dis       Date:  1994-01       Impact factor: 9.079

Review 8.  Viral studies of chronic fatigue syndrome.

Authors:  J A Levy
Journal:  Clin Infect Dis       Date:  1994-01       Impact factor: 9.079

9.  A controlled clinical trial with a specifically configured RNA drug, poly(I).poly(C12U), in chronic fatigue syndrome.

Authors:  D R Strayer; W A Carter; I Brodsky; P Cheney; D Peterson; P Salvato; C Thompson; M Loveless; D E Shapiro; W Elsasser
Journal:  Clin Infect Dis       Date:  1994-01       Impact factor: 9.079

Review 10.  Cytokines in autoimmune disorders.

Authors:  M Feldmann; F M Brennan; R Maini
Journal:  Int Rev Immunol       Date:  1998       Impact factor: 5.311
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  39 in total

1.  NF-kappaB activation stimulates transcription and replication of retrovirus XMRV in human B-lineage and prostate carcinoma cells.

Authors:  Shuhei Sakakibara; Kaori Sakakibara; Giovanna Tosato
Journal:  J Virol       Date:  2011-01-26       Impact factor: 5.103

Review 2.  Evidence for the presence of immune dysfunction in chronic fatigue syndrome.

Authors:  Benjamin H Natelson; Mohammad H Haghighi; Nicholas M Ponzio
Journal:  Clin Diagn Lab Immunol       Date:  2002-07

Review 3.  A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome.

Authors:  Gerwyn Morris; Michael Maes
Journal:  Metab Brain Dis       Date:  2012-06-21       Impact factor: 3.584

Review 4.  Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms?

Authors:  S E Kim; L Chang
Journal:  Neurogastroenterol Motil       Date:  2012-08-02       Impact factor: 3.598

Review 5.  A neuroinflammatory model for acute fatigue during exercise.

Authors:  Nicole T Vargas; Frank Marino
Journal:  Sports Med       Date:  2014-11       Impact factor: 11.136

Review 6.  Cytokines in immune function and sleep regulation.

Authors:  James M Krueger; Jeannine A Majde; David M Rector
Journal:  Handb Clin Neurol       Date:  2011

7.  Fatigue is associated with high circulating leptin levels in chronic hepatitis C.

Authors:  T Piche; E Gelsi; S M Schneider; X Hébuterne; J Giudicelli; B Ferrua; C Laffont; S Benzaken; P Hastier; M L Montoya; F Longo; P Rampal; A Tran
Journal:  Gut       Date:  2002-09       Impact factor: 23.059

8.  Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers.

Authors:  David Benjamin Fischer; Arsani Hany William; Adam Campbell Strauss; Elizabeth R Unger; Leonard Jason; Gailen D Marshall; Jordan D Dimitrakoff
Journal:  Fatigue       Date:  2014-06-01

9.  A gene signature for post-infectious chronic fatigue syndrome.

Authors:  John W Gow; Suzanne Hagan; Pawel Herzyk; Celia Cannon; Peter O Behan; Abhijit Chaudhuri
Journal:  BMC Med Genomics       Date:  2009-06-25       Impact factor: 3.063

10.  Association of C-reactive protein and interleukin-6 with new-onset fatigue in the Whitehall II prospective cohort study.

Authors:  H J Cho; M Kivimäki; J E Bower; M R Irwin
Journal:  Psychol Med       Date:  2012-11-14       Impact factor: 7.723
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