Literature DB >> 1053433

Half-life of C1INH in hereditary angioneurotic oedema (HAE).

D Brackertz, E Isler, F Kueppers.   

Abstract

The half-life of 125I labelled C1INH was determined in patients with HAE and normal controls. There was no significant difference between these two groups. The half-life in the HAE patients was 67.7 hr +/- 4.9 hr (s.d.) and in the normals 64 hr +/- 1.4 hr (s.d.). This finding is consistent with a defect in synthesis as an explanation of the low serum C1INH levels in HAE patients.

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Year:  1975        PMID： 1053433     DOI： 10.1111/j.1365-2222.1975.tb01839.x

Source DB:  PubMed          Journal:  Clin Allergy        ISSN： 0009-9090


  4 in total

1.  Behavior in vivo of normal and dysfunctional C1 inhibitor in normal subjects and patients with hereditary angioneurotic edema.

Authors:  M Quastel; R Harrison; M Cicardi; C A Alper; F S Rosen
Journal:  J Clin Invest       Date:  1983-04       Impact factor: 14.808

2.  Cinryze as the first approved C1 inhibitor in the USA for the treatment of hereditary angioedema: approval, efficacy and safety.

Authors:  Michael Lunn; Carah Santos; Timothy Craig
Journal:  J Blood Med       Date:  2010-08-24

3.  The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update.

Authors:  Marcus Maurer; Markus Magerl; Stephen Betschel; Werner Aberer; Ignacio J Ansotegui; Emel Aygören-Pürsün; Aleena Banerji; Noémi-Anna Bara; Isabelle Boccon-Gibod; Konrad Bork; Laurence Bouillet; Henrik Balle Boysen; Nicholas Brodszki; Paula J Busse; Anette Bygum; Teresa Caballero; Mauro Cancian; Anthony J Castaldo; Danny M Cohn; Dorottya Csuka; Henriette Farkas; Mark Gompels; Richard Gower; Anete S Grumach; Guillermo Guidos-Fogelbach; Michihiro Hide; Hye-Ryun Kang; Allen P Kaplan; Constance H Katelaris; Sorena Kiani-Alikhan; Wei-Te Lei; Richard F Lockey; Hilary Longhurst; William Lumry; Andrew MacGinnitie; Alejandro Malbran; Inmaculada Martinez Saguer; Juan José Matta Campos; Alexander Nast; Dinh Nguyen; Sandra A Nieto-Martinez; Ruby Pawankar; Jonathan Peter; Grzegorz Porebski; Nieves Prior; Avner Reshef; Marc Riedl; Bruce Ritchie; Farrukh Rafique Sheikh; William B Smith; Peter J Spaeth; Marcin Stobiecki; Elias Toubi; Lilian Agnes Varga; Karsten Weller; Andrea Zanichelli; Yuxiang Zhi; Bruce Zuraw; Timothy Craig
Journal:  World Allergy Organ J       Date:  2022-04-07       Impact factor: 5.516

4.  Pharmacokinetics of plasma-derived C1-esterase inhibitor after subcutaneous versus intravenous administration in subjects with mild or moderate hereditary angioedema: the PASSION study.

Authors:  Inmaculada Martinez-Saguer; Marco Cicardi; Chiara Suffritti; Eva Rusicke; Emel Aygören-Pürsün; Hildegard Stoll; Tanja Rossmanith; Annette Feussner; Uwe Kalina; Wolfhart Kreuz
Journal:  Transfusion       Date:  2013-11-24       Impact factor: 3.157
  4 in total

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