Literature DB >> 10534275

Use of Bacille Calmette-Guèrin (BCG) in multiple sclerosis.

G Ristori1, M G Buzzi, U Sabatini, E Giugni, S Bastianello, F Viselli, C Buttinelli, S Ruggieri, C Colonnese, C Pozzilli, M Salvetti.   

Abstract

We studied the effect of Bacille Calmette-Guerin (BCG) vaccine as an immunomodulator in MS. According to the guidelines for clinical trials in MS, a single crossover, MRI-monitored trial was performed in 14 patients with relapsing-remitting MS. After treatment, MRI activity was significantly reduced. No major adverse effects were reported. Adjuvant therapy with BCG vaccine was safe and merits study in MS.

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Year:  1999        PMID： 10534275     DOI： 10.1212/wnl.53.7.1588

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  38 in total

Review 1.  Vaccination against infection in patients with multiple sclerosis.

Authors:  Micha Loebermann; Alexander Winkelmann; Hans-Peter Hartung; Hartmut Hengel; Emil C Reisinger; Uwe K Zettl
Journal:  Nat Rev Neurol       Date:  2012-01-24       Impact factor: 42.937

Review 2.  Mycobacteria-induced suppression of autoimmunity in the central nervous system.

Authors:  JangEun Lee; Matyas Sandor; Erika Heninger; Zsuzsanna Fabry
Journal:  J Neuroimmune Pharmacol       Date:  2010-03-24       Impact factor: 4.147

Review 3.  [Vaccination and multiple sclerosis].

Authors:  M Löbermann; A Winkelmann; E C Reisinger; U K Zettl
Journal:  Nervenarzt       Date:  2010-02       Impact factor: 1.214

4.  Infection in systemic lupus erythematosus: friend or foe?

Authors:  Lisa Francis; Andras Perl
Journal:  Int J Clin Rheumtol       Date:  2010-02-01

Review 5.  Vaccines in Multiple Sclerosis.

Authors:  Eric M L Williamson; Salim Chahin; Joseph R Berger
Journal:  Curr Neurol Neurosci Rep       Date:  2016-04       Impact factor: 5.081

6.  Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

Authors:  Goran Laćan; Hoa Dang; Blake Middleton; Marcus A Horwitz; Jide Tian; William P Melega; Daniel L Kaufman
Journal:  J Neurosci Res       Date:  2013-08-01       Impact factor: 4.164

7.  Infection with Mycobacterium bovis BCG diverts traffic of myelin oligodendroglial glycoprotein autoantigen-specific T cells away from the central nervous system and ameliorates experimental autoimmune encephalomyelitis.

Authors:  Diane L Sewell; Emily K Reinke; Dominic O Co; Laura H Hogan; Robert B Fritz; Matyas Sandor; Zsuzsa Fabry
Journal:  Clin Diagn Lab Immunol       Date:  2003-07

8.  BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner.

Authors:  Valerie Acm Koeken; L Charlotte J de Bree; Vera P Mourits; Simone Jcfm Moorlag; Jona Walk; Branko Cirovic; Rob Jw Arts; Martin Jaeger; Helga Dijkstra; Heidi Lemmers; Leo Ab Joosten; Christine S Benn; Reinout van Crevel; Mihai G Netea
Journal:  J Clin Invest       Date:  2020-10-01       Impact factor: 14.808

9.  Mycobacterium bovis bacille Calmette-Guérin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner.

Authors:  JangEun Lee; Emily K Reinke; Alla L Zozulya; Matyas Sandor; Zsuzsanna Fabry
Journal:  J Immunol       Date:  2008-11-01       Impact factor: 5.422

10.  Effects of Bacille Calmette-Guerin after the first demyelinating event in the CNS.

Authors:  Giovanni Ristori; Silvia Romano; Stefania Cannoni; Andrea Visconti; Emanuele Tinelli; Laura Mendozzi; Pietro Cecconi; Roberta Lanzillo; Mario Quarantelli; Carla Buttinelli; Claudio Gasperini; Marco Frontoni; Giulia Coarelli; Domenico Caputo; Vincenzo Bresciamorra; Nicola Vanacore; Carlo Pozzilli; Marco Salvetti
Journal:  Neurology       Date:  2013-12-04       Impact factor: 9.910
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