Literature DB >> 10534008

Nuclear proliferation in syncytia during avian reovirus replication.

Y Tsukamoto1, T Kotani, K Kohama, S Sakuma, F Sasaki.   

Abstract

Cultured chick embryonic fibroblasts formed syncytia after infection with avian reovirus (ARV) strain 58-132. Mitotic figures were occasionally observed within the syncytia. In addition, many nuclei in the syncytia incorporated 5-bromo-2'-deoxyuridine (BrdU), a DNA replication marker, indicating that they were in the S-phase of the cell cycle. These observations suggested that the nuclei within ARV-induced syncytia originated from nuclear endomitosis without cell division, as well as from cell fusion.

Entities:  

Mesh：

Year:  1999        PMID： 10534008      PMCID： PMC1189565     

Source DB:  PubMed          Journal:  Can J Vet Res        ISSN： 0830-9000            Impact factor:   1.310


  6 in total

1.  Pathogenic characteristics of highly virulent avian reovirus, strain 58-132, isolated from a chicken with tenosynovitis.

Authors:  K Takase; H Nishikawa; F Nonaka; S Yamada
Journal:  Nihon Juigaku Zasshi       Date:  1985-08

2.  Avian reovirus-induced syncytium formation is independent of infectious progeny virus production and enhances the rate, but is not essential, for virus-induced cytopathology and virus egress.

Authors:  R Duncan; Z Chen; S Walsh; S Wu
Journal:  Virology       Date:  1996-10-15       Impact factor: 3.616

3.  Characterization of avian reovirus-induced cell fusion: the role of viral structural proteins.

Authors:  Y Ni; R F Ramig
Journal:  Virology       Date:  1993-06       Impact factor: 3.616

4.  Deduced amino acid sequences at the fusion protein cleavage site of Newcastle disease viruses showing variation in antigenicity and pathogenicity.

Authors:  M S Collins; J B Bashiruddin; D J Alexander
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

5.  Avian infectious laryngo-tracheitis in Egypt. I. Epidemiology, virus isolation and identification.

Authors:  H H Tantawi; A M El Batrawi; M A Bastami; Y I Youssef; M M Fawzia
Journal:  Vet Res Commun       Date:  1983-09       Impact factor: 2.459

6.  Avian reovirus sigma C protein contains a putative fusion sequence and induces fusion when expressed in mammalian cells.

Authors:  M B Theophilos; J A Huang; I H Holmes
Journal:  Virology       Date:  1995-04-20       Impact factor: 3.616
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.