Literature DB >> 10532100

[Immunomodulator Cycloferon in the comprehensive treatment of patients with acute non-lymphoblastic leukemia].

S I Moiseev1, K M Abdulkadyrov, L N Bubnova, T V Glazanova, O E Rozanova, I E Pavlova, V A Balashova, A L Kovalenko.   

Abstract

The therapeutic benefit and action of the immunomodulator Cycloferon were evaluated in patients with acute non-lymphoblastic leukemia. When administered in conjunction with chemotherapy during first complete remission, it reduced both early-onset relapse frequency and degree of cytostatic-induced immune deficiency. The drug's action is mediated by changes taking place in cytokine and interferon synthesis.

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Year:  1999        PMID: 10532100

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  1 in total

1.  Meglumine acridone acetate, the ionic salt of CMA and N-methylglucamine, induces apoptosis in human PBMCs via the mitochondrial pathway.

Authors:  Marina A Plotnikova; Sergey A Klotchenko; Artem A Kiselev; Andrey N Gorshkov; Anna-Polina S Shurygina; Kirill A Vasilyev; Urszula Uciechowska-Kaczmarzyk; Sergey A Samsonov; Alexey L Kovalenko; Andrey V Vasin
Journal:  Sci Rep       Date:  2019-12-03       Impact factor: 4.379

  1 in total

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