Literature DB >> 10531387

Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors.

U Savas1, K J Griffin, E F Johnson.   

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Year:  1999        PMID： 10531387     DOI： 10.1124/mol.56.5.851

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


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  13 in total

1.  The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated.

Authors:  Ambra Pozzi; Vlad Popescu; Shilin Yang; Shaojun Mei; Mingjian Shi; Satu M Puolitaival; Richard M Caprioli; Jorge H Capdevila
Journal:  J Biol Chem       Date:  2010-02-23       Impact factor: 5.157

Review 2.  Guide to drug porphyrogenicity prediction and drug prescription in the acute porphyrias.

Authors:  Stig Thunell; Erik Pomp; Atle Brun
Journal:  Br J Clin Pharmacol       Date:  2007-06-19       Impact factor: 4.335

3.  An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

Authors:  W Xie; A Radominska-Pandya; Y Shi; C M Simon; M C Nelson; E S Ong; D J Waxman; R M Evans
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

4.  A Molecular Aspect in the Regulation of Drug Metabolism: Does PXR-Induced Enzyme Expression Always Lead to Functional Changes in Drug Metabolism?

Authors:  Yuan Wei; Chenxiao Tang; Vinayak Sant; Song Li; Samuel M Poloyac; Wen Xie
Journal:  Curr Pharmacol Rep       Date:  2016-05-04

Review 5.  The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis.

Authors:  Jiezhong Chen; Kong-Nan Zhao; Chen Chen
Journal:  Ann Transl Med       Date:  2014-01

6.  Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.

Authors:  W Xie; J L Barwick; C M Simon; A M Pierce; S Safe; B Blumberg; P S Guzelian; R M Evans
Journal:  Genes Dev       Date:  2000-12-01       Impact factor: 11.361

7.  Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

Authors:  Kiyoshi Nakagawa; Vijaykumar R Holla; Yuan Wei; Wen-Hui Wang; Arnaldo Gatica; Shouzou Wei; Shaojun Mei; Crystal M Miller; Dae Ryong Cha; Edward Price; Roy Zent; Ambra Pozzi; Matthew D Breyer; Youfei Guan; John R Falck; Michael R Waterman; Jorge H Capdevila
Journal:  J Clin Invest       Date:  2006-05-11       Impact factor: 14.808

8.  CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR).

Authors:  C Handschin; M Podvinec; U A Meyer
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-26       Impact factor: 11.205

9.  Use of transgenic mice in UDP-glucuronosyltransferase (UGT) studies.

Authors:  Zhimin Ou; Min Huang; Lizi Zhao; Wen Xie
Journal:  Drug Metab Rev       Date:  2010-02       Impact factor: 4.518

10.  Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers.

Authors:  Tamara R Knight; Supratim Choudhuri; Curtis D Klaassen
Journal:  Toxicol Sci       Date:  2008-08-22       Impact factor: 4.849
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