Literature DB >> 10531023

Axis development: the mouse becomes a dachshund.

J M Gad1, P P Tam.   

Abstract

Targeted deletion of the gene for GDF11, a novel member of the TGFbeta family, has been found to cause an increase in the number of thoracic and lumbar vertebrae in the mouse. This is the first hint that a secreted factor may influence the specification of segment identity.

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Year:  1999        PMID: 10531023     DOI: 10.1016/S0960-9822(00)80013-5

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  6 in total

1.  Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.

Authors:  S Paul Oh; Chang-Yeol Yeo; Youngjae Lee; Heindrich Schrewe; Malcolm Whitman; En Li
Journal:  Genes Dev       Date:  2002-11-01       Impact factor: 11.361

Review 2.  The versatility and paradox of GDF 11.

Authors:  A Jamaiyar; W Wan; D M Janota; M K Enrick; W M Chilian; L Yin
Journal:  Pharmacol Ther       Date:  2017-02-14       Impact factor: 12.310

3.  Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.

Authors:  Olov Andersson; Eva Reissmann; Carlos F Ibáñez
Journal:  EMBO Rep       Date:  2006-07-14       Impact factor: 8.807

4.  Species and strain differences in rodent sciatic nerve anatomy: implications for studies of neuropathic pain.

Authors:  Marcel Rigaud; Geza Gemes; Marie-Elizabeth Barabas; Donna I Chernoff; Stephen E Abram; Cheryl L Stucky; Quinn H Hogan
Journal:  Pain       Date:  2008-03-07       Impact factor: 6.961

Review 5.  GDF11 Implications in Cancer Biology and Metabolism. Facts and Controversies.

Authors:  Arturo Simoni-Nieves; Monserrat Gerardo-Ramírez; Gibrán Pedraza-Vázquez; Lisette Chávez-Rodríguez; Leticia Bucio; Verónica Souza; Roxana U Miranda-Labra; Luis E Gomez-Quiroz; María Concepción Gutiérrez-Ruiz
Journal:  Front Oncol       Date:  2019-10-15       Impact factor: 6.244

Review 6.  Deciphering Myostatin's Regulatory, Metabolic, and Developmental Influence in Skeletal Diseases.

Authors:  Catherine L Omosule; Charlotte L Phillips
Journal:  Front Genet       Date:  2021-03-29       Impact factor: 4.599

  6 in total

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