Literature DB >> 10529827

Virus resistance and gene silencing: killing the messenger.

.   

Abstract

On occassion, virus-derived transgenes in plants can be poorly expressed and yet provide excellent virus resistance, and transgene constructs designed to supplement the expression of endogenous genes can have the effect of co-suppressing themselves and the endogenous genes. These two phenomena appear to result from the same post-transcriptional silencing mechanism, which operates by targeted-RNA degradation. Recent research into RNA-mediated virus resistance and co-suppression has provided insights into the interactions between plant viruses and their hosts, and spawned several models to explain the phenomenon.

Year:  1999        PMID： 10529827     DOI： 10.1016/s1360-1385(99)01493-4

Source DB:  PubMed          Journal:  Trends Plant Sci        ISSN： 1360-1385            Impact factor:   18.313


  18 in total

1.  Methods of double-stranded RNA-mediated gene inactivation in Arabidopsis and their use to define an essential gene in methionine biosynthesis.

Authors:  J Z Levin; A J de Framond; A Tuttle; M W Bauer; P B Heifetz
Journal:  Plant Mol Biol       Date:  2000-12       Impact factor: 4.076

2.  High-efficiency silencing of a beta-glucuronidase gene in rice is correlated with repetitive transgene structure but is independent of DNA methylation.

Authors:  M B Wang; P M Waterhouse
Journal:  Plant Mol Biol       Date:  2000-05       Impact factor: 4.076

3.  Transgene silencing of invertedly repeated transgenes is released upon deletion of one of the transgenes involved.

Authors:  S De Buck; M Van Montagu; A Depicker
Journal:  Plant Mol Biol       Date:  2001-07       Impact factor: 4.076

Review 4.  Plant DNA viruses and gene silencing.

Authors:  S N Covey; N S Al-Kaff
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 5.  RNA degradation and models for post-transcriptional gene-silencing.

Authors:  F Meins
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 6.  Plants as bioreactors for protein production: avoiding the problem of transgene silencing.

Authors:  C De Wilde; H Van Houdt; S De Buck; G Angenon; G De Jaeger; A Depicker
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 7.  Role of inverted DNA repeats in transcriptional and post-transcriptional gene silencing.

Authors:  M W Muskens; A P Vissers; J N Mol; J M Kooter
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 8.  Transgene silencing by the host genome defense: implications for the evolution of epigenetic control mechanisms in plants and vertebrates.

Authors:  M A Matzke; M F Mette; A J Matzke
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

9.  High molecular weight RNAs and small interfering RNAs induce systemic posttranscriptional gene silencing in plants.

Authors:  Ulrich Klahre; Patrice Crété; Sabrina A Leuenberger; Victor A Iglesias; Frederick Meins
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-14       Impact factor: 11.205

10.  Cauliflower mosaic virus gene VI product N-terminus contains regions involved in resistance-breakage, self-association and interactions with movement protein.

Authors:  Michael Hapiak; Yongzhong Li; Keli Agama; Shaddy Swade; Genevieve Okenka; Jessica Falk; Sushant Khandekar; Gaurav Raikhy; Alisha Anderson; Justin Pollock; Wendy Zellner; James Schoelz; Scott M Leisner
Journal:  Virus Res       Date:  2008-10-28       Impact factor: 3.303
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.