Literature DB >> 10529149

Two cases of methotrexate induced lymphomas in rheumatoid arthritis: an association with increased serum IgE.

H Kono1, S Inokuma, Y Matsuzaki, H Nakayama, J Yamazaki, T Hishima, Y Maeda.   

Abstract

We describe 2 patients with rheumatoid arthritis (RA) in whom non-Hodgkin's lymphomas developed during low dose pulsed methotrexate (MTX) treatment. The tumors regressed after discontinuation of MTX with no additional treatment. Serum levels of IgE increased concomitantly with the development of lymphoma, and decreased along with the regression of the lymphoma in both patients. These 2 cases and a review of the literature suggest that measuring serum IgE may have a predictive value for monitoring lymphoma in patients with RA treated with MTX.

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Year:  1999        PMID： 10529149

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  6 in total

1.  Reversible Epstein-Barr virus-negative lymphadenopathy and bone marrow involved by Hodgkin's lymphoma in a rheumatoid arthritis patient undergoing long-term treatment with low-dose methotrexate: a case report and review of the literature.

Authors:  Annika M Svensson; Erica R Jacobson; David Ospina; Barbara H Tindle
Journal:  Int J Hematol       Date:  2006-01       Impact factor: 2.490

2.  Mature T/NK-cell lymphoproliferative disease and Epstein-Barr virus infection are more frequent in patients with rheumatoid arthritis treated with methotrexate.

Authors:  Seiji Kondo; Kazuki Tanimoto; Kozue Yamada; Goichi Yoshimoto; Eiichi Suematsu; Tomoaki Fujisaki; Yumi Oshiro; Kazuo Tamura; Morishige Takeshita; Seiichi Okamura
Journal:  Virchows Arch       Date:  2013-03-14       Impact factor: 4.064

Review 3.  Spontaneous remission of "methotrexate-associated lymphoproliferative disorders" after discontinuation of immunosuppressive treatment for autoimmune disease. Review of the literature.

Authors:  Rita Rizzi; Paola Curci; Mario Delia; Erminia Rinaldi; Antonia Chiefa; Giorgina Specchia; Vincenzo Liso
Journal:  Med Oncol       Date:  2008-05-07       Impact factor: 3.064

4.  Methotrexate-induced acute leukemia: report of three cases and review of the literature.

Authors:  Khalid A Al-Anazi; Khalid I Eltayeb; Mohammed Bakr; Fahad I Al-Mohareb
Journal:  Clin Med Case Rep       Date:  2009-07-31

5.  Epstein-Barr-Virus-Infected CD15 (Lewis X)-Positive Hodgkin-Lymphoma-Like B Cells in Patients with Rheumatoid Arthritis.

Authors:  Hirotake Inomata; Masami Takei; Hiroyuki Nakamura; Shigeyoshi Fujiwara; Hidetaka Shiraiwa; Noboru Kitamura; Shunsei Hirohata; Hiroyuki Masuda; Jin Takeuchi; Shigemasa Sawada
Journal:  Open Rheumatol J       Date:  2009-09-07

6.  A Putative Case of Methotrexate-Related Lymphoma: Clinical Course and PET/CT Findings.

Authors:  Rachel C Jankowitz; James Ganon; Todd Blodgett; Christine Garcia; Samuel Jacobs
Journal:  Case Rep Med       Date:  2009-12-23
  6 in total

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