Literature DB >> 10528978

Relationships between the modulus of elasticity and tensile strength for pharmaceutical drugs and excipients.

R J Roberts1, R C Rowe.   

Abstract

The relationship between the modulus of elasticity and tensile strength for a variety of pharmaceutical drugs and excipients has been explored as a means of generating algorithms for use in computer simulations and expert systems. From literature data two equations have been developed to enable the formulator, from knowledge of one property, to predict the other with a reasonable degree of accuracy. Such relationships are invaluable for use in computer simulation programs or formulation expert systems, enabling formulators to screen potential formulations quickly without the need for extensive experimental work.

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Year:  1999        PMID: 10528978     DOI: 10.1211/0022357991773438

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  2 in total

1.  A quantitative correlation of the effect of density distributions in roller-compacted ribbons on the mechanical properties of tablets using ultrasonics and X-ray tomography.

Authors:  Ilgaz Akseli; Srinivas Iyer; Hwahsiung P Lee; Alberto M Cuitiño
Journal:  AAPS PharmSciTech       Date:  2011-06-28       Impact factor: 3.246

2.  A Multi-variate Mathematical Model for Simulating the Granule Size Distribution in Roller Compaction-Milling Process.

Authors:  Hossein Amini; Ilgaz Akseli
Journal:  AAPS PharmSciTech       Date:  2021-03-10       Impact factor: 3.246

  2 in total

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